Nonionic surfactant vesicles as a novel drug delivery system for increasing the oral bioavailability of Ginsenoside Rb1
Sign Up to like & getrecommendations! Published in 2021 at "Food bioscience"
DOI: 10.1016/j.fbio.2021.101064
Abstract: Abstract In the present study, a novel nonionic surfactant vesicles (NSVs) system consisting of cholesterol, Tween 80 and Span 80 was developed for the delivery of Ginsenoside Rb1 with an improved oral bioavailability. The prepared… read more here.
Keywords: rb1; nonionic surfactant; ginsenoside rb1; oral bioavailability ... See more keywords
Ginsenoside Rb1 ameliorates autophagy via the AMPK/mTOR pathway in renal tubular epithelial cells in vitro and in vivo.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2020.07.060
Abstract: Although ginsenoside Rb1 (G-Rb1) has exerted an inhibitory effect on renal fibrosis and progression of chronic kidney disease (CKD), its mechanism remains unknown. This study aims to explore the anti-fibrosis effect of G-Rb1 in unilateral… read more here.
Keywords: treatment; ampk mtor; effect; ginsenoside rb1 ... See more keywords
Ginsenoside Rb1 is an immune-stimulatory agent with antiviral activity against enterovirus 71.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2020.113401
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE According to the theory of traditional Chinese medicine, the main pathogenesis of severe hand, foot and mouth disease (HFMD) is that the heat and wet poisons are deeply trapped in the viscera, which… read more here.
Keywords: rb1 immune; antiviral activity; ginsenoside rb1; immune stimulatory ... See more keywords
Ginsenoside Rb1 inhibits monoiodoacetate-induced osteoarthritis in postmenopausal rats through prevention of cartilage degradation
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Ginseng Research"
DOI: 10.1016/j.jgr.2020.01.004
Abstract: Background Ginsenoside Rb1 (G-Rb1), one of the major active compounds in Panax ginseng, has already been shown to reduce inflammation in various diseases. Osteoarthritis (OA) has traditionally been considered a degenerative disease with degradation of… read more here.
Keywords: degradation; mia induced; ginsenoside rb1; rb1 ... See more keywords
Ginsenoside Rb1 promotes the growth of mink hair follicle via PI3K/AKT/GSK-3β signaling pathway.
Sign Up to like & getrecommendations! Published in 2019 at "Life sciences"
DOI: 10.1016/j.lfs.2019.05.033
Abstract: AIMS Hair follicles play a critical role in the process of hair growth. The dermal papilla cells (DPCs) are an important component in the hair follicle regeneration and growth. This study investigated the effects of… read more here.
Keywords: hair follicles; hair; mink hair; ginsenoside rb1 ... See more keywords
Impact of ginsenoside Rb1 on gut microbiome and associated changes in pharmacokinetics in rats
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-72225-1
Abstract: Ginsenoside Rb1 exhibits a wide range of biological activities, and gut microbiota is considered the main metabolic site for Rb1. However, the impact of gut microbiota on the pharmacokinetics of Rb1 are still uncertain. In… read more here.
Keywords: ginsenoside rb1; gut microbiota; gut microbiome; changes pharmacokinetics ... See more keywords
Ginsenoside Rb1 reduces oxidative/carbonyl stress damage and ameliorates inflammation in the lung of streptozotocin-induced diabetic rats
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutical Biology"
DOI: 10.1080/13880209.2022.2140168
Abstract: Abstract Context Ginsenoside Rb1 (Rb1) is a biologically active component of ginseng [Panax ginseng C.A. Meyer (Araliaceae)]. Objective This study determined the underlying mechanisms of Rb1 treatment that acted on diabetes-injured lungs in diabetic rats.… read more here.
Keywords: ginsenoside rb1; diabetic rats; rb1; lung ... See more keywords
Ginsenoside Rb1 promotes intestinal epithelial wound healing through extracellular signal‐regulated kinase and Rho signaling
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Gastroenterology and Hepatology"
DOI: 10.1111/jgh.14532
Abstract: Daikenchuto, a traditional Japanese herbal medicine, has been reported to exhibit anti‐inflammatory effects against intestinal inflammation. However, whether daikenchuto has a therapeutic effect against intestinal mucosal injuries remains unclear. Thus, the aim of this study… read more here.
Keywords: wound healing; intestinal epithelial; promotes intestinal; ginsenoside rb1 ... See more keywords
Ginsenoside Rb1 affects mitochondrial Ca2+ transport and inhibits fat deposition and fibrosis by regulating the wnt signaling pathway to treat rotator cuff tears via docking with SFRP1
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Medicine"
DOI: 10.1186/s10020-024-01009-0
Abstract: Rotator cuff tears (RCTs) are among the most common musculoskeletal disorders that affect quality of life. This study aimed to investigate the efficacy of ginsenoside Rb1 in RCTs and the mechanisms involved. First, a fibrotic… read more here.
Keywords: treatment; rotator cuff; ginsenoside rb1; sfrp1 ... See more keywords
Carbon quantum dots of ginsenoside Rb1 for application in a mouse model of intracerebral Hemorrhage
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Nanobiotechnology"
DOI: 10.1186/s12951-024-02368-w
Abstract: After intracerebral hemorrhage (ICH) occurs, the overproduction of reactive oxygen species (ROS) and iron ion overload are the leading causes of secondary damage. Removing excess iron ions and ROS in the meningeal system can effectively… read more here.
Keywords: intracerebral hemorrhage; quantum dots; carbon quantum; ginsenoside rb1 ... See more keywords
Ginsenoside Rb1 Inhibits the Proliferation of Lung Cancer Cells by Inducing the Mitochondrial-mediated Apoptosis Pathway.
Sign Up to like & getrecommendations! Published in 2024 at "Anti-cancer agents in medicinal chemistry"
DOI: 10.2174/0118715206299212240304142047
Abstract: BACKGROUND Lung cancer is one of the more common malignant tumors posing a great threat to human life, and it is very urgent to find safe and effective therapeutic drugs. The antitumor effect of ginsenosides… read more here.
Keywords: lung cancer; cancer; cancer cells; ginsenoside rb1 ... See more keywords