Nonionic surfactant vesicles as a novel drug delivery system for increasing the oral bioavailability of Ginsenoside Rb1
Sign Up to like & getrecommendations! Published in 2021 at "Food bioscience"
DOI: 10.1016/j.fbio.2021.101064
Abstract: Abstract In the present study, a novel nonionic surfactant vesicles (NSVs) system consisting of cholesterol, Tween 80 and Span 80 was developed for the delivery of Ginsenoside Rb1 with an improved oral bioavailability. The prepared… read more here.
Keywords: rb1; nonionic surfactant; ginsenoside rb1; oral bioavailability ... See more keywords
Ginsenoside Rb1 ameliorates autophagy via the AMPK/mTOR pathway in renal tubular epithelial cells in vitro and in vivo.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2020.07.060
Abstract: Although ginsenoside Rb1 (G-Rb1) has exerted an inhibitory effect on renal fibrosis and progression of chronic kidney disease (CKD), its mechanism remains unknown. This study aims to explore the anti-fibrosis effect of G-Rb1 in unilateral… read more here.
Keywords: treatment; ampk mtor; effect; ginsenoside rb1 ... See more keywords
Ginsenoside Rb1 is an immune-stimulatory agent with antiviral activity against enterovirus 71.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2020.113401
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE According to the theory of traditional Chinese medicine, the main pathogenesis of severe hand, foot and mouth disease (HFMD) is that the heat and wet poisons are deeply trapped in the viscera, which… read more here.
Keywords: rb1 immune; antiviral activity; ginsenoside rb1; immune stimulatory ... See more keywords
Ginsenoside Rb1 inhibits monoiodoacetate-induced osteoarthritis in postmenopausal rats through prevention of cartilage degradation
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Ginseng Research"
DOI: 10.1016/j.jgr.2020.01.004
Abstract: Background Ginsenoside Rb1 (G-Rb1), one of the major active compounds in Panax ginseng, has already been shown to reduce inflammation in various diseases. Osteoarthritis (OA) has traditionally been considered a degenerative disease with degradation of… read more here.
Keywords: degradation; mia induced; ginsenoside rb1; rb1 ... See more keywords
Ginsenoside Rb1 promotes the growth of mink hair follicle via PI3K/AKT/GSK-3β signaling pathway.
Sign Up to like & getrecommendations! Published in 2019 at "Life sciences"
DOI: 10.1016/j.lfs.2019.05.033
Abstract: AIMS Hair follicles play a critical role in the process of hair growth. The dermal papilla cells (DPCs) are an important component in the hair follicle regeneration and growth. This study investigated the effects of… read more here.
Keywords: hair follicles; hair; mink hair; ginsenoside rb1 ... See more keywords
Ginsenoside Rb1 reduces oxidative/carbonyl stress damage and ameliorates inflammation in the lung of streptozotocin-induced diabetic rats
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutical Biology"
DOI: 10.1080/13880209.2022.2140168
Abstract: Abstract Context Ginsenoside Rb1 (Rb1) is a biologically active component of ginseng [Panax ginseng C.A. Meyer (Araliaceae)]. Objective This study determined the underlying mechanisms of Rb1 treatment that acted on diabetes-injured lungs in diabetic rats.… read more here.
Keywords: ginsenoside rb1; diabetic rats; rb1; lung ... See more keywords
Ginsenoside Rb1 promotes intestinal epithelial wound healing through extracellular signal‐regulated kinase and Rho signaling
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Gastroenterology and Hepatology"
DOI: 10.1111/jgh.14532
Abstract: Daikenchuto, a traditional Japanese herbal medicine, has been reported to exhibit anti‐inflammatory effects against intestinal inflammation. However, whether daikenchuto has a therapeutic effect against intestinal mucosal injuries remains unclear. Thus, the aim of this study… read more here.
Keywords: wound healing; intestinal epithelial; promotes intestinal; ginsenoside rb1 ... See more keywords
Ginsenoside Rb1 Suppresses AOM/DSS-Induced Colon Carcinogenesis.
Sign Up to like & getrecommendations! Published in 2023 at "Anti-cancer agents in medicinal chemistry"
DOI: 10.2174/1871520623666230119092735
Abstract: BACKGROUND Colorectal cancer (CRC) is the third most common cancer world-wide. Current treatments, including surgery, radiotherapy, and chemotherapy, are limited by severe side effects and the development of resistance. OBJECTIVE Therefore, it is important to… read more here.
Keywords: aom dss; ginsenoside rb1; cancer;
Ginsenoside Rb1 attenuates lipopolysaccharide-induced neural damage in the brain of mice via regulating the dysfunction of microglia and astrocytes.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of integrative neuroscience"
DOI: 10.31083/j.jin2004084
Abstract: The purpose of our research was to evaluate whether ginsenoside Rb1 has neuroprotective effects against lipopolysaccharide (LPS)-induced brain injury. ICR mice were intraperitoneally (i.p.) injected with 20 or 40 mg/kg Rb1 or saline for 7… read more here.
Keywords: mice; ginsenoside rb1; brain; lps induced ... See more keywords
Mannose-decorated ginsenoside Rb1 albumin nanoparticles for targeted anti-inflammatory therapy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.962380
Abstract: Ginsenoside Rb1 is a potential anti-inflammatory natural molecule, but its therapeutic efficacy was tremendously hampered by the low solubility and non-targeted delivery. In this study, we innovatively developed a mannose (Man)-modified albumin bovine serum albumin… read more here.
Keywords: ginsenoside rb1; rb1; inflammatory therapy; anti inflammatory ... See more keywords
Ginsenoside Rb1 Improves Metabolic Disorder in High-Fat Diet-Induced Obese Mice Associated With Modulation of Gut Microbiota
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.826487
Abstract: Gut microbiota plays an important role in metabolic homeostasis. Previous studies demonstrated that ginsenoside Rb1 might improve obesity-induced metabolic disorders through regulating glucose and lipid metabolism in the liver and adipose tissues. Due to low… read more here.
Keywords: ginsenoside rb1; rb1; modulation gut; gut microbiota ... See more keywords