Ginsenoside Rg1 protects H9c2 cells against nutritional stress‐induced injury via aldolase /AMPK/PINK1 signalling
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29150
Abstract: Insufficient nutrients supply will greatly affect the function of cardiac myocytes. The adaptive responses of cardiac myocytes to nutritional stress are not fully known. Ginsenoside Rg1 is one of the most pharmacologically active components in… read more here.
Keywords: ginsenoside rg1; h9c2 cells; aldolase; nutritional stress ... See more keywords
Ginsenoside Rg1 ameliorates sepsis‐induced acute kidney injury by inhibiting ferroptosis in renal tubular epithelial cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.1a0422-211r
Abstract: Acute kidney injury (AKI) represents a prevailing complication of sepsis, and its onset involves ferroptosis. Ginsenoside Rg1 exerts a positive effect on kidney diseases. This study explored the action of ginsenoside Rg1 in sepsis‐induced AKI… read more here.
Keywords: sepsis; rg1; ferroptosis renal; kidney ... See more keywords
Ginsenoside Rg1 protects mice against streptozotocin-induced type 1 diabetic by modulating the NLRP3 and Keap1/Nrf2/HO-1 pathways.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2019.172801
Abstract: Ginseng has been traditionally used to treat diabetes mellitus (DM) in China. Ginsenoside Rg1 is a major active ingredient in processed ginseng, which elicits proven biological and pharmacological effects. Although a correlation between nucleotide-binding oligomerization… read more here.
Keywords: ginsenoside rg1; keap1 nrf2; rg1 protects; nlrp3 keap1 ... See more keywords
Ginsenoside Rg1 protects against hind‐limb ischemia reperfusion induced lung injury via NF‐&kgr;B/COX‐2 signaling pathway
Sign Up to like & getrecommendations! Published in 2018 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2018.04.040
Abstract: Background/aims: Ginsenoside Rg1 is regarded as the primary bioactive ingredient in Panax notoginseng that has been well recognized for its protective effects against ischemia/reperfusion (IR) injury. However, the mechanisms still remain elusive. Our study aims… read more here.
Keywords: ginsenoside rg1; rg1; hind limb; group ... See more keywords
Ginsenoside Rg1 prevent and treat inflammatory diseases: A review.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.106805
Abstract: Ginseng has been used as reinforcing drugs or for traditional Chinese medicine in aging, inflammation, stress, diabetes mellitus, hepatic diseases and cancer. The aim of this current review is to provide an integrative overview of… read more here.
Keywords: ginsenoside rg1; diseases review; prevent treat; inflammatory diseases ... See more keywords
Ginsenoside Rg1 enhances the healing of injured tendon in achilles tendinitis through the activation of IGF1R signaling mediated by oestrogen receptor
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Ginseng Research"
DOI: 10.1016/j.jgr.2021.08.005
Abstract: Abstract Background During the pathogenesis of tendinopathy, the chronic inflammation caused by the injury and apoptosis leads to the generation of scars. Ginsenoside Rg1 (Rg1) is extracted from ginseng and has anti-inflammatory effects. Rg1 is… read more here.
Keywords: ginsenoside rg1; rg1; achilles tendinitis; igf1r ... See more keywords
Transcriptome analysis reveals the efficacy of ginsenoside-Rg1 in the treatment of nonalcoholic fatty liver disease.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.118986
Abstract: AIMS Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver disease and lacks for safe and effective drug to therapy completely. Ginsenoside-Rg1 is one of the main components of ginseng and has been proved… read more here.
Keywords: ginsenoside rg1; fatty liver; rg1; treatment ... See more keywords
Ginsenoside Rg1 attenuation of neurogenesis disorder and neuronal apoptosis in the rat hippocampus after spinal cord injury may involve brain-derived neurotrophic factor/extracellular signal-regulated kinase signaling
Sign Up to like & getrecommendations! Published in 2023 at "NeuroReport"
DOI: 10.1097/wnr.0000000000001891
Abstract: Objective We previously demonstrated that spinal cord injury (SCI) induced hippocampus injury and depression in rodents. Ginsenoside Rg1 effectively prevents neurodegenerative disorders. Here, we investigated the effects of ginsenoside Rg1 on the hippocampus after SCI.… read more here.
Keywords: rg1; sci; rat; ginsenoside rg1 ... See more keywords
Effects of Ginsenoside Rg1 on the Biological Activity of Human Periodontal Ligament Cells
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DOI: 10.1155/2022/7576359
Abstract: , Objective. To investigate the effect of ginsenoside Rg1 on the biological activity of primary cultured human periodontal ligament cells (PDLC). Methods. The effects of ginsenoside Rg1 on the proliferation activity, protein synthesis, and alkaline… read more here.
Keywords: activity; ligament cells; ginsenoside rg1; periodontal ligament ... See more keywords
Ginsenoside Rg1 Protects Cardiomyocytes Against Hypoxia/Reoxygenation Injury via Activation of Nrf2/HO-1 Signaling and Inhibition of JNK
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DOI: 10.1159/000484578
Abstract: Background/Aims: Excessive reactive oxygen species (ROS) disturb the physiology of H9c2 cells, which is regarded as a major cause of H9c2 cardiomyocyte apoptosis. Ginsenoside Rg1 is the main active extract of ginseng, which has important… read more here.
Keywords: ginsenoside rg1; h9c2 cells; rg1; physiology ... See more keywords
Ginsenoside Rg1 inhibits dietary-induced obesity and improves obesity-related glucose metabolic disorders
Sign Up to like & getrecommendations! Published in 2018 at "Brazilian Journal of Medical and Biological Research"
DOI: 10.1590/1414-431x20177139
Abstract: Obesity and its consequent type 2 diabetes are significant threats to global health. Emerging evidence indicates that ginsenosides from ginseng (Panax ginseng) have anti-diabetic activity. We hypothesized that ginsenosides Rg1 could suppress dietary-induced obesity and… read more here.
Keywords: ginsenoside rg1; dietary induced; obesity related; induced obesity ... See more keywords