Exploring the Effect of Ginsenoside Rh1 in a Sleep Deprivation‐Induced Mouse Memory Impairment Model
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DOI: 10.1002/ptr.5797
Abstract: Panax ginseng C.A. Meyer (Araliaceae) has been used in traditional Chinese medicine for enhancing cognition for thousands of years. Ginsenoside Rh1, a constituent of ginseng root, as with other constituents, has memory‐improving effects in normal… read more here.
Keywords: sleep deprivation; ginsenoside rh1; memory impairment; memory ... See more keywords
Ginsenoside Rh1 regulates gastric cancer cell biological behaviours and transplanted tumour growth in nude mice via the TGF‐β/Smad pathway
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Pharmacology and Physiology"
DOI: 10.1111/1440-1681.13708
Abstract: Gastric cancer (GC) is one of the most prevalent malignancies of the digestive tract. Ginsenoside Rh1 was reported to exert effects on GC. The current study set out to explore the mechanism underlying Ginsenoside Rh1… read more here.
Keywords: ginsenoside rh1; tgf smad; rh1; smad pathway ... See more keywords
Ginsenoside Rh1 protects human endothelial cells against lipopolysaccharide-induced inflammatory injury through inhibiting TLR2/4-mediated STAT3, NF-κB, and ER stress signaling pathways.
Sign Up to like & getrecommendations! Published in 2022 at "Life sciences"
DOI: 10.2139/ssrn.4122052
Abstract: AIM Endothelial cell (EC) dysfunction initiates atherosclerosis by inducing inflammatory cytokines and adhesion molecules. Herein, we investigated the role of ginsenoside Rh1 (Rh1) in lipopolysaccharide (LPS)-induced EC dysfunction. MAIN METHODS The inhibitory effect of Rh1… read more here.
Keywords: ginsenoside rh1; lps induced; stress signaling; signaling pathways ... See more keywords
Ginsenoside Rh1 ameliorates the asthma and allergic inflammation via inhibiting Akt, MAPK, and NF-κB signaling pathways in vitro and in vivo.
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DOI: 10.2139/ssrn.4333539
Abstract: AIMS Overproduction of pro-inflammatory cytokines and its-mediated immune cell infiltration play a crucial role in asthma progression. In this study, we investigated the role of ginsenoside Rh1 (Rh1) in ovalbumin (OVA)/lipopolysaccharide (LPS)-induced allergic asthma both… read more here.
Keywords: vitro vivo; inflammation; ginsenoside rh1; signaling pathways ... See more keywords
Ginsenoside Rh1 Exerts Neuroprotective Effects by Activating the PI3K/Akt Pathway in Amyloid-β Induced SH-SY5Y Cells
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DOI: 10.3390/app11125654
Abstract: Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by the accumulation of β-amyloid plaques and hyperphosphorylated tau proteins in the brain. Cell signaling pathways such as PI3K/Akt are known to play an essential role in… read more here.
Keywords: amyloid; pi3k akt; ginsenoside rh1; cell ... See more keywords
Ginsenoside Rh1 Induces MCF-7 Cell Apoptosis and Autophagic Cell Death through ROS-Mediated Akt Signaling
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DOI: 10.3390/cancers13081892
Abstract: Simple Summary Breast cancer (BC) is the most common cause of cancer-related deaths among women worldwide, and its incidence has been increasing. However, current therapeutic approaches, such as chemotherapy, radiation, and hormonal therapy, have become… read more here.
Keywords: cancer; ginsenoside rh1; cell apoptosis; cell ... See more keywords