Hypothalamic and brainstem glucose-dependent insulinotropic polypeptide receptor neurons employ distinct mechanisms to affect feeding.
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DOI: 10.1172/jci.insight.164921
Abstract: Central glucose-dependent insulinotropic polypeptide (GIP) receptor (GIPR) signaling is critical in GIP-based therapeutics' ability to lower body weight, but pathways leveraged by GIPR pharmacology in the brain remain incompletely understood. We explored the role of… read more here.
Keywords: gipr neurons; glucose dependent; pharmacology; insulinotropic polypeptide ... See more keywords