Dephosphorylation of Girdin by PP2A inhibits breast cancer metastasis.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.03.167
Abstract: Dysfunction of Girdin plays a crucial role in the development of a variety of tumors. Phosphorylated regulation of Girdin has been studied extensively. However, how Girdin is dephosphorylated remains unclear. In this study, we report… read more here.
Keywords: dephosphorylation; girdin; pp2a; breast cancer ... See more keywords
Girdin Knockdown Increases Gemcitabine Chemosensitivity to Pancreatic Cancer by Modulating Autophagy
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.618764
Abstract: Chemotherapy is crucial for the treatment of pancreatic cancer (PC). Gemcitabine (GEM) as the first-line chemotherapy drug has a high resistance rate. Increasing the sensitivity of gemcitabine is currently the objectives and challenges of this… read more here.
Keywords: chemosensitivity; girdin; gemcitabine chemosensitivity; pancreatic cancer ... See more keywords
Engulfment of platelets delays endothelial cell aging via girdin and its phosphorylation.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of molecular medicine"
DOI: 10.3892/ijmm.2018.3685
Abstract: Endothelial cells are critical in angiogenesis and maintain the homeostasis of the blood‑brain barrier (BBB). Platelets (PLTs) are essential in vascular biology, including angiogenesis. The present study aimed to investigate the effect of PLTs on… read more here.
Keywords: engulfment; microscopy; endothelial cells; girdin ... See more keywords