GS-0976 Reduces Hepatic Steatosis and Fibrosis Markers in Patients With Nonalcoholic Fatty Liver Disease.
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DOI: 10.1053/j.gastro.2018.07.027
Abstract: BACKGROUND & AIMS De novo lipogenesis is increased in livers of patients with nonalcoholic steatohepatitis (NASH). Acetyl-coenzyme carboxylase catalyzes the rate-limiting step in this process. We evaluated the safety and efficacy of GS-0976, an inhibitor… read more here.
Keywords: hepatic steatosis; fibrosis; liver; given 0976 ... See more keywords