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Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-21611-7
Abstract: Atrial fibrillation (AF) is the most common arrhythmia. In 2014, two new meta-GWAS identified 5 AF loci, including the NEURL locus, GJA1 locus, CAND2 locus, and TBX5 locus in the European ancestry populations and the…
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Keywords:
atrial fibrillation;
neurl gja1;
gja1;
cux2 ... See more keywords
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Published in 2022 at "Stem cells"
DOI: 10.1093/stmcls/sxac017
Abstract: The development of the vertebrate retina relies on complex regulatory mechanisms to achieve its characteristic layered morphology containing multiple neuronal cell types. While connexin 43 (CX43) is not expressed by mature retinal neurons mutations in…
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Keywords:
absence connexin;
gja1;
retinal organoids;
retinal progenitor ... See more keywords
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Published in 2022 at "Cardiovascular Therapeutics"
DOI: 10.1155/2022/9966306
Abstract: Background Deep vein thrombosis (DVT) is the third most prevalent vascular disease worldwide. MicroRNAs (miRNAs) play regulatory roles in functions of endothelial progenitor cells (EPCs), which is becoming a promising therapeutic choice for thrombus resolution.…
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Keywords:
vein thrombosis;
endothelial progenitor;
gja1;
mir 206 ... See more keywords
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Published in 2022 at "Journal of Orthopaedic Surgery and Research"
DOI: 10.1186/s13018-022-03044-1
Abstract: Background A large amount of evidence suggested that miRNA was involved in the progression of intervertebral disk degeneration (IDD). The purpose of our study was to explore the function and potential mechanism of miR-206/GJA1 axis…
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Keywords:
idd;
gja1;
disk degeneration;
targeting gja1 ... See more keywords
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Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.867358
Abstract: Connexin 43 (Cx43) is the primary gap junction protein of mammalian heart ventricles and is encoded by the gene Gja1 which has a single coding exon and therefore cannot be spliced. We previously identified that…
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Keywords:
cx43;
20k mitochondrial;
gja1;
mitochondrial dynamics ... See more keywords
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Published in 2021 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2021.12024
Abstract: It has been reported that microRNAs (miRs) contribute to several biological functions and are associated with drug resistance in various types of cancer. However, to the best of our knowledge, whether miR-613 can affect cisplatin…
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Keywords:
mir 613;
gja1;
lung cancer;
cancer ... See more keywords