Articles with "gkn1" as a keyword



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Gastrokine 1 protein is a potential theragnostic target for gastric cancer

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Published in 2018 at "Gastric Cancer"

DOI: 10.1007/s10120-018-0828-8

Abstract: BackgroundGastrokine 1 (GKN1) plays important roles in maintaining mucosal homeostasis, and in regulating cell proliferation and differentiation. Here, we determined whether GKN1 is a potential theragnostic marker for gastric cancer.MethodsWe identified GKN1 binding proteins using… read more here.

Keywords: gkn1; gastric cancer; cell proliferation; western blot ... See more keywords
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Role of human GKN1 on APP processing in gastric cancer.

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Published in 2017 at "Biochimie"

DOI: 10.1016/j.biochi.2017.02.007

Abstract: Gastrokine 1 (GKN1) is highly expressed in gastric tissue and is secreted into the stomach but is not expressed in gastric cancer. GKN1 belongs to the BRICHOS domain family and plays a major role in… read more here.

Keywords: app processing; gastric cancer; gkn1; human gkn1 ... See more keywords
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Gastrokine-1, an anti-amyloidogenic protein secreted by the stomach, regulates diet-induced obesity

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Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-88928-8

Abstract: Obesity and its sequelae have a major impact on human health. The stomach contributes to obesity in ways that extend beyond its role in digestion, including through effects on the microbiome. Gastrokine-1 (GKN1) is an… read more here.

Keywords: amyloidogenic protein; gkn1; secreted stomach; obesity ... See more keywords
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The role and diagnostic potential of gastrokine 1 in gastric cancer

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Published in 2019 at "Cancer Management and Research"

DOI: 10.2147/cmar.s194949

Abstract: Introduction Gene for gastrokine 1 (GKN1) was identified as one of the most significant in gastric cancer and indicated as a potential therapeutic target. Aim The aim was a review of literature reports concerning the… read more here.

Keywords: cancer; gastric cancer; diagnostic potential; gkn1 ... See more keywords