Antimicrobial peptide GL13K immobilized onto SLA-treated titanium by silanization: antibacterial effect against methicillin-resistant Staphylococcus aureus (MRSA)
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DOI: 10.1039/d1ra04974g
Abstract: Infection is the main reason for implant failure, and the incidence of drug-resistant bacterial infection has increased in recent years. Further, methicillin-resistant Staphylococcus aureus (MRSA)-related implant infection has become a serious worldwide threat. New strategies,… read more here.
Keywords: gl13k; methicillin resistant; spectroscopy; staphylococcus aureus ... See more keywords
The Effects of Titanium Surfaces Modified with an Antimicrobial Peptide GL13K by Silanization on Polarization, Anti-Inflammatory, and Proinflammatory Properties of Macrophages
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DOI: 10.1155/2020/2327034
Abstract: The polarization of macrophages and its anti-inflammatory and proinflammatory properties play a significant role in host response after implant placement to determine the outcome of osseointegration and long-term survival. In the previous study, we immobilized… read more here.
Keywords: anti inflammatory; inflammatory proinflammatory; proinflammatory properties; titanium ... See more keywords
A D-enantiomer of the antimicrobial peptide GL13K evades antimicrobial resistance in the Gram positive bacteria Enterococcus faecalis and Streptococcus gordonii
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DOI: 10.1371/journal.pone.0194900
Abstract: Antimicrobial peptides represent an alternative to traditional antibiotics that may be less susceptible to bacterial resistance mechanisms by directly attacking the bacterial cell membrane. However, bacteria have a variety of defense mechanisms that can prevent… read more here.
Keywords: gram positive; peptide; positive bacteria; gordonii ... See more keywords