Articles with "gla protein" as a keyword



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The impact of a key nutraceutical complex on chondrocyte cells and matrix Gla protein expression

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Published in 2021 at "Biocatalysis and agricultural biotechnology"

DOI: 10.1016/j.bcab.2021.101930

Abstract: Abstract Osteoarthritis (OA) is the most common type of arthritis among adults, which is associated with cartilage breakdown. Chondrocytes are the only type of cell in articular cartilage that secrete extracellular matrix (ECM). Therefore, to… read more here.

Keywords: expression; chondrocyte cells; impact key; chondrocyte ... See more keywords
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Matrix Gla protein is an independent predictor of both intimal and medial vascular calcification in chronic kidney disease

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Published in 2020 at "Scientific Reports"

DOI: 10.1038/s41598-020-63013-8

Abstract: Matrix Gla protein (MGP) is a potent inhibitor of vascular calcification (VC) and requires carboxylation by vitamin K to exert calcification inhibition. Chronic kidney disease (CKD) patients undergo early vascular aging often involving extensive VC.… read more here.

Keywords: vascular calcification; chronic kidney; calcification; gla protein ... See more keywords
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Corrigendum to: Association between matrix Gla protein and ulcerative colitis according to DNA microarray data

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Published in 2020 at "Gastroenterology Report"

DOI: 10.1093/gastro/goaa013

Abstract: [This corrects the article DOI: 10.1093/gastro/goz038.][This corrects the article DOI: 10.1093/gastro/goz038.]. read more here.

Keywords: association matrix; gla protein; matrix gla; ulcerative colitis ... See more keywords
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Association between matrix Gla protein and ulcerative colitis according to DNA microarray data

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Published in 2020 at "Gastroenterology Report"

DOI: 10.1093/gastro/goz038

Abstract: Abstract Background Matrix Gla protein (MGP) is a secreted protein contributed to the immunomodulatory functions of mesenchymal stromal cells. Microarray profiling found a significantly higher expression level of the extracellular matrix gene MGP in patients… read more here.

Keywords: matrix gla; mgp; colitis; gla protein ... See more keywords

THE ASSOCIATION OF URINARY MATRIX GLA PROTEIN WITH CIRCULATING INACTIVE MATRIX GLA PROTEIN, RENAL FUNCTION AND MORTALITY RISK: A POPULATION STUDY

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Published in 2022 at "Journal of Hypertension"

DOI: 10.1097/01.hjh.0000836492.07827.fe

Abstract: Objective: Matrix Gla protein (MGP) is a small protein for the protection of vascular calcification. High circulating desphospho-uncarboxylated MGP (dp-ucMGP), indicative of poor vitamin K status, has been associated with renal dysfunction and mortality. However,… read more here.

Keywords: gla protein; urinary mgp; mortality; matrix gla ... See more keywords
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Role of Matrix Gla Protein in the Complex Network of Coronary Artery Disease: A Comprehensive Review

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Published in 2021 at "Life"

DOI: 10.3390/life11080737

Abstract: Coronary artery disease (CAD) is widely recognized as one of the most important clinical entities. In recent years, a large body of accumulated data suggest that coronary artery calcification, a process highly prevalent in patients… read more here.

Keywords: artery; coronary artery; gla protein; matrix gla ... See more keywords
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Circulating Levels of Dephosphorylated-Uncarboxylated Matrix Gla Protein in Patients with Acute Coronary Syndrome

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Published in 2021 at "Molecules"

DOI: 10.3390/molecules26041108

Abstract: Vascular calcification contributes to the pathogenesis of coronary artery disease while matrix Gla protein (MGP) was recently identified as a potent inhibitor of vascular calcification. MGP fractions, such as dephosphorylated-uncarboxylated MGP (dp-ucMGP), lack post-translational modifications… read more here.

Keywords: ucmgp levels; patients acute; gla protein; matrix gla ... See more keywords
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Effect of 6-Month Vitamin D Supplementation on Plasma Matrix Gla Protein in Older Adults

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Published in 2019 at "Nutrients"

DOI: 10.3390/nu11020231

Abstract: Vitamin D supplementation has been widely promoted to restore 25-hydroxyvitamin D concentrations; however, experimental evidence suggests a nutrient interaction with vitamin K. We assessed the effects of 1200 IU vitamin D3 per day versus placebo… read more here.

Keywords: gla protein; matrix gla; vitamin supplementation; placebo ... See more keywords