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Published in 2021 at "Biocatalysis and agricultural biotechnology"
DOI: 10.1016/j.bcab.2021.101930
Abstract: Abstract Osteoarthritis (OA) is the most common type of arthritis among adults, which is associated with cartilage breakdown. Chondrocytes are the only type of cell in articular cartilage that secrete extracellular matrix (ECM). Therefore, to…
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Keywords:
expression;
chondrocyte cells;
impact key;
chondrocyte ... See more keywords
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Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-63013-8
Abstract: Matrix Gla protein (MGP) is a potent inhibitor of vascular calcification (VC) and requires carboxylation by vitamin K to exert calcification inhibition. Chronic kidney disease (CKD) patients undergo early vascular aging often involving extensive VC.…
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Keywords:
vascular calcification;
chronic kidney;
calcification;
gla protein ... See more keywords
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Published in 2020 at "Gastroenterology Report"
DOI: 10.1093/gastro/goaa013
Abstract: [This corrects the article DOI: 10.1093/gastro/goz038.][This corrects the article DOI: 10.1093/gastro/goz038.].
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Keywords:
association matrix;
gla protein;
matrix gla;
ulcerative colitis ... See more keywords
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Published in 2020 at "Gastroenterology Report"
DOI: 10.1093/gastro/goz038
Abstract: Abstract Background Matrix Gla protein (MGP) is a secreted protein contributed to the immunomodulatory functions of mesenchymal stromal cells. Microarray profiling found a significantly higher expression level of the extracellular matrix gene MGP in patients…
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Keywords:
matrix gla;
mgp;
colitis;
gla protein ... See more keywords
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Published in 2022 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000836492.07827.fe
Abstract: Objective: Matrix Gla protein (MGP) is a small protein for the protection of vascular calcification. High circulating desphospho-uncarboxylated MGP (dp-ucMGP), indicative of poor vitamin K status, has been associated with renal dysfunction and mortality. However,…
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Keywords:
gla protein;
urinary mgp;
mortality;
matrix gla ... See more keywords
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Published in 2021 at "Life"
DOI: 10.3390/life11080737
Abstract: Coronary artery disease (CAD) is widely recognized as one of the most important clinical entities. In recent years, a large body of accumulated data suggest that coronary artery calcification, a process highly prevalent in patients…
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Keywords:
artery;
coronary artery;
gla protein;
matrix gla ... See more keywords
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Published in 2021 at "Molecules"
DOI: 10.3390/molecules26041108
Abstract: Vascular calcification contributes to the pathogenesis of coronary artery disease while matrix Gla protein (MGP) was recently identified as a potent inhibitor of vascular calcification. MGP fractions, such as dephosphorylated-uncarboxylated MGP (dp-ucMGP), lack post-translational modifications…
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Keywords:
ucmgp levels;
patients acute;
gla protein;
matrix gla ... See more keywords
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Published in 2019 at "Nutrients"
DOI: 10.3390/nu11020231
Abstract: Vitamin D supplementation has been widely promoted to restore 25-hydroxyvitamin D concentrations; however, experimental evidence suggests a nutrient interaction with vitamin K. We assessed the effects of 1200 IU vitamin D3 per day versus placebo…
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Keywords:
gla protein;
matrix gla;
vitamin supplementation;
placebo ... See more keywords