The influence of repeated frowning and smiling on corrugator muscle activity and wrinkles between eyebrows
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-024-84121-9
Abstract: Like the lines themselves, concerns about facial wrinkles, particularly glabellar lines - the prominent furrows between the eyebrows - intensify with age. These lines can inadvertently convey negative emotions due to their association with negative… read more here.
Keywords: repeated frowning; corrugator muscle; corrugator; wrinkles eyebrows ... See more keywords
Long-term safety and efficacy of MBA-P01 for the treatment of glabellar lines: results from a multicenter, repeated-dose, open-label extension study
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Dermatological Treatment"
DOI: 10.1080/09546634.2024.2418919
Abstract: Abstract Purpose Following the introduction of new type of botulinum toxin (MBA-P01), a recent phase 3 study demonstrated that MBA-P01 showed comparable efficacy and safety to onabotulinumtoxin A for reducing glabellar lines. The primary objective… read more here.
Keywords: mba p01; treatment; safety; study ... See more keywords
The Second of Two One-Year, Multicenter, Open-Label, Repeat-Dose, Phase II Safety Studies of PrabotulinumtoxinA for the Treatment of Moderate to Severe Glabellar Lines in Adult Patients.
Sign Up to like & getrecommendations! Published in 2021 at "Aesthetic surgery journal"
DOI: 10.1093/asj/sjaa382
Abstract: BACKGROUND PrabotulinumtoxinA is a 900-kDa botulinum toxin type A produced by Clostridium botulinum. OBJECTIVES The authors sought to investigate the safety of prabotulinumtoxinA for treatment of glabellar lines. METHODS This was a multicenter, open-label, repeat-dose,… read more here.
Keywords: severe glabellar; treatment; safety; study drug ... See more keywords
The First of Two One-Year, Multicenter, Open-Label, Repeat-Dose, Phase II Safety Studies of PrabotulinumtoxinA for the Treatment of Moderate to Severe Glabellar Lines in Adult Patients.
Sign Up to like & getrecommendations! Published in 2021 at "Aesthetic surgery journal"
DOI: 10.1093/asj/sjaa383
Abstract: BACKGROUND PrabotulinumtoxinA is a 900-kDa botulinum toxin type A produced by Clostridium botulinum. OBJECTIVES The authors sought to investigate the safety of prabotulinumtoxinA for treatment of glabellar lines. METHODS This was a multicenter, open-label, repeat-dose,… read more here.
Keywords: severe glabellar; treatment; safety; study drug ... See more keywords
Efficacy and Safety of DaxibotulinumtoxinA for Injection in the Treatment of Glabellar Lines by Age and Race: Subgroup Analysis of the SAKURA Clinical Trials
Sign Up to like & getrecommendations! Published in 2022 at "Aesthetic Surgery Journal"
DOI: 10.1093/asj/sjac246
Abstract: Abstract Background DaxibotulinumtoxinA for Injection (DAXI) is a novel botulinum toxin type A formulation approved for the treatment of glabellar lines. The efficacy, safety, and extended duration of response of DAXI 40 U for glabellar… read more here.
Keywords: age race; age; glabellar lines; efficacy safety ... See more keywords
Integrative Assessment for Optimizing Aesthetic Outcomes When Treating Glabellar Lines With Botulinum Toxin Type A: An Appreciation of the Role of the Frontalis.
Sign Up to like & getrecommendations! Published in 2022 at "Aesthetic surgery journal"
DOI: 10.1093/asj/sjac267
Abstract: Despite the perception that treatment of glabellar lines with botulinum toxin A (BoNTA) is straightforward, the reality is that the glabellar region contains a number of interrelated muscles. In order to avoid adverse outcomes, practitioners… read more here.
Keywords: role frontalis; lines botulinum; glabellar lines; botulinum toxin ... See more keywords
A Retrospective Study of Chinese-Specific Glabellar Contraction Patterns
Sign Up to like & getrecommendations! Published in 2019 at "Dermatologic Surgery"
DOI: 10.1097/dss.0000000000001808
Abstract: BACKGROUND Botulinum toxin has been widely accepted as safe and effective for the treatment of glabellar lines, and previous studies have classified glabellar contraction patterns into 5 categories. OBJECTIVE To classify the glabellar contraction patterns… read more here.
Keywords: glabellar contraction; classification systems; contraction patterns; glabellar lines ... See more keywords
Efficacy, Safety, and Subject Satisfaction After AbobotulinumtoxinA Treatment for Moderate to Severe Glabellar Lines.
Sign Up to like & getrecommendations! Published in 2019 at "Dermatologic Surgery"
DOI: 10.1097/dss.0000000000002013
Abstract: BACKGROUND The aesthetic use of botulinum toxins is widely accepted in routine treatment of glabellar lines. OBJECTIVE To strengthen existing efficacy and safety data, and examine subject satisfaction concerning abobotulinumtoxinA (ABO) treatment for moderate to… read more here.
Keywords: efficacy safety; subject satisfaction; treatment; satisfaction ... See more keywords
Efficacy and Safety of a New Botulinum Toxin (HU-014) Versus Existing Onabotulinumtoxin A in Subjects With Moderate to Severe Glabellar Lines.
Sign Up to like & getrecommendations! Published in 2020 at "Dermatologic Surgery"
DOI: 10.1097/dss.0000000000002789
Abstract: BACKGROUND Recently, the safety of a new botulinum toxin (HU-014) was confirmed through animal experiments. The evaluation of the efficacy and safety of this newly introduced botulinum toxin is required considering the risk of adverse… read more here.
Keywords: existing onabotulinumtoxin; botulinum toxin; glabellar lines; safety ... See more keywords
PrabotulinumtoxinA for Treatment of Millennials With Moderate to Severe Glabellar Lines: Post Hoc Analyses of the Phase III Clinical Study Data
Sign Up to like & getrecommendations! Published in 2022 at "Dermatologic Surgery"
DOI: 10.1097/dss.0000000000003456
Abstract: Supplemental Digital Content is Available in the Text. BACKGROUND The use of esthetic products by millennials is increasing, yet published clinical trial data in this population are limited. OBJECTIVE To compare the efficacy and safety… read more here.
Keywords: severe glabellar; glabellar lines; moderate severe; post hoc ... See more keywords
The efficacy and complications of a new technique of Abobotulinum‐toxin A (Dysport) injection in patients with glabellar lines
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cosmetic Dermatology"
DOI: 10.1111/jocd.12529
Abstract: Abobotulinum‐ toxin A is used extensively for the treatment of frown (glabellar) lines. read more here.
Keywords: efficacy complications; abobotulinum toxin; complications new; glabellar lines ... See more keywords