New antifungal ent-labdane diterpenes against Candida glabrata produced by microbial transformation of ent-polyalthic acid.
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DOI: 10.1016/j.bioorg.2019.103560
Abstract: Candida glabrata, the most common non-albicans Candida species and one of the primary causes of candidemia, exhibits decreased susceptibility to azoles and more recently to echinocandins. Polyalthic acid 1, a furan diterpene, has been shown… read more here.
Keywords: glabrata produced; ent; produced microbial; polyalthic acid ... See more keywords