Edodes Cultured Extract Regulates Immune Stress During Puberty and Modulates MicroRNAs Involved in Mammary Gland Development and Breast Cancer Suppression
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Medicine"
DOI: 10.1002/cam4.70277
Abstract: Immune stressors, such as lipopolysaccharides (LPS), profoundly affect microbiota balance, leading to gut dysbiosis. This imbalance disrupts the metabolic phenotype and structural integrity of the gut, increasing intestinal permeability. During puberty, a critical surge in… read more here.
Keywords: cancer; breast cancer; mammary gland; gland development ... See more keywords
Ingestion of Bt rice pollen does not reduce the survival or hypopharyngeal gland development of Apis mellifera adults.
Sign Up to like & getrecommendations! Published in 2017 at "Environmental toxicology and chemistry"
DOI: 10.1002/etc.3647
Abstract: Because of its ecological and economic importance, the honey bee Apis mellifera is commonly used to assess the environmental risk of insect-resistant, genetically modified plants. In the present study, feeding-exposure experiments were used to determine… read more here.
Keywords: rice; hypopharyngeal gland; gland development; survival hypopharyngeal ... See more keywords
Repression of endogenous retroviruses prevents antiviral immune response and is required for mammary gland development.
Sign Up to like & getrecommendations! Published in 2021 at "Cell stem cell"
DOI: 10.1016/j.stem.2021.04.030
Abstract: The role of heterochromatin in cell fate specification during development is unclear. We demonstrate that loss of the lysine 9 of histone H3 (H3K9) methyltransferase G9a in the mammary epithelium results in de novo chromatin… read more here.
Keywords: stem cell; mammary gland; endogenous retroviruses; gland development ... See more keywords
Insight into mammary gland development and tumor progression in an E2F5 conditional knockout mouse model
Sign Up to like & getrecommendations! Published in 2024 at "Oncogene"
DOI: 10.1038/s41388-024-03172-4
Abstract: Development of breast cancer is linked to altered regulation of mammary gland developmental processes. A better understanding of normal mammary gland development can thus reveal possible mechanisms of how normal cells are re-programmed to become… read more here.
Keywords: mammary gland; gland development; knockout; development ... See more keywords
Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-13363-3
Abstract: Wnt signaling is critical for directing epithelial gland development within the uterine lining to ensure successful gestation in adults. Wnt-dependent, Lgr5-expressing stem/progenitor cells are essential for the development of glandular epithelia in the intestine and… read more here.
Keywords: uterine gland; wnt dependent; gland development; stem ... See more keywords
Parasitism by Nycteribiidae and Streblidae Flies (Diptera) of a Malagasy Fruit Bat (Pteropodidae): Effects of Body Size and Throat Gland Development on Parasite Abundance
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Medical Entomology"
DOI: 10.1093/jme/tjw245
Abstract: Abstract We examined the possible effects of host body size and throat gland development on the abundance of bloodfeeding nycteribiid and streblid flies parasitizing a Malagasy fruit bat, Rousettus madagascariensis G. Grandidier, 1928. Data were… read more here.
Keywords: throat gland; abundance; gland development; body size ... See more keywords
Abstract B53: Psychosocial stress exposure results in inhibition of mammary gland development and increased mammary stem cells in a rat model of breast cancer
Sign Up to like & getrecommendations! Published in 2018 at "Carcinogenesis"
DOI: 10.1158/1538-7755.disp17-b53
Abstract: Exposure to unremitting psychosocial stressors common to underserved populations (i.e., social marginalization and isolation, economic uncertainty, and racism) manifest in physiologic changes that are associated with highly aggressive mammary cancer. Many environmental exposures that influence… read more here.
Keywords: cancer; mammary gland; stress; gland development ... See more keywords
Establishment of goat mammary organoid cultures modeling the mammary gland development and lactation
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Animal Science and Biotechnology"
DOI: 10.1186/s40104-024-01084-7
Abstract: Although several cell culture systems have been developed to investigate the function of the mammary gland in dairy livestock, they have potential limitations, such as the loss of alveolar structure or genetic and phenotypic differences… read more here.
Keywords: lactation; mammary gland; culture; gland development ... See more keywords
Chronic estrus disrupts uterine gland development and homeostasis.
Sign Up to like & getrecommendations! Published in 2022 at "Endocrinology"
DOI: 10.1210/endocr/bqac011
Abstract: Female mice homozygous for an engineered Gnrhr E90K mutation have reduced gonadotropin-releasing hormone signaling, leading to infertility. Their ovaries have numerous antral follicles but no corpora lutea, indicating a block to ovulation. These mutants have… read more here.
Keywords: development; pubertal uterine; post pubertal; gland development ... See more keywords
SAT-342 Macrophage-Derived C/EBPb During Mammary Gland Development and Breast Cancer Progression
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Endocrine Society"
DOI: 10.1210/js.2019-sat-342
Abstract: Abstract Macrophages are necessary in mammary gland development to drive ductal elongation and have been shown to promote cancer metastasis. Our laboratory has previously shown that macrophages are recruited to pre-invasive lesions to induce localized… read more here.
Keywords: progression; cancer; breast cancer; mammary gland ... See more keywords
Canonical PRC2 function is essential for mammary gland development and affects chromatin compaction in mammary organoids
Sign Up to like & getrecommendations! Published in 2018 at "PLoS Biology"
DOI: 10.1371/journal.pbio.2004986
Abstract: Distinct transcriptional states are maintained through organization of chromatin, resulting from the sum of numerous repressive and active histone modifications, into tightly packaged heterochromatin versus more accessible euchromatin. Polycomb repressive complex 2 (PRC2) is the… read more here.
Keywords: gland development; mammary gland; prc2; mammary organoids ... See more keywords