Trend-Based Progression Analysis for Examination of the Topography of Rates of Retinal Nerve Fiber Layer Thinning in Glaucoma
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Ophthalmology"
DOI: 10.1001/jamaophthalmol.2016.5111
Abstract: Importance Measurement of the rates of retinal nerve fiber layer (RNFL) thinning has consisted primarily of the circumpapillary RNFL profile. This study reports the rates of RNFL thinning over the 6 × 6 mm2 RNFL thickness map… read more here.
Keywords: topography; rnfl thinning; rnfl; glaucoma ... See more keywords
Genotype-Phenotype Associations of IL6 and PRG4 With Conjunctival Fibrosis After Glaucoma Surgery
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DOI: 10.1001/jamaophthalmol.2017.3407
Abstract: Importance Postsurgical fibrosis is a critical determinant of the long-term success of glaucoma surgery, but no reliable biomarkers are currently available to stratify the risk of scarring. Objective To compare the clinical phenotype of patients… read more here.
Keywords: glaucoma surgery; phenotype; fibrosis; glaucoma ... See more keywords
Association Between Lamina Cribrosa Defects and Progressive Retinal Nerve Fiber Layer Loss in Glaucoma
Sign Up to like & getrecommendations! Published in 2019 at "JAMA Ophthalmology"
DOI: 10.1001/jamaophthalmol.2018.6941
Abstract: Importance Certain features of the lamina cribrosa may be associated with increased risk of glaucoma progression. Objectives To compare the rates of retinal nerve fiber layer (RNFL) thinning in patients with open-angle glaucoma with or… read more here.
Keywords: lamina cribrosa; rnfl; glaucoma; rate ... See more keywords
Nailfold Capillaroscopy of Resting Peripheral Blood Flow in Exfoliation Glaucoma and Primary Open-Angle Glaucoma.
Sign Up to like & getrecommendations! Published in 2019 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2019.0434
Abstract: Importance Systemic blood flow alterations have been described using video nailfold capillaroscopy (NFC) in high-tension glaucoma (HTG) and normal-tension glaucoma (NTG) variants of primary open-angle glaucoma (POAG). To date, no previous studies have explored alterations… read more here.
Keywords: blood flow; glaucoma; resting peripheral; nailfold capillaroscopy ... See more keywords
Assessment of a Segmentation-Free Deep Learning Algorithm for Diagnosing Glaucoma From Optical Coherence Tomography Scans.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2019.5983
Abstract: Importance Conventional segmentation of the retinal nerve fiber layer (RNFL) is prone to errors that may affect the accuracy of spectral-domain optical coherence tomography (SD-OCT) scans in detecting glaucomatous damage. Objective To develop a segmentation-free… read more here.
Keywords: glaucoma; segmentation; segmentation free; rnfl thickness ... See more keywords
Estimated Utility of the Short-term Assessment of Glaucoma Progression Model in Clinical Practice.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2021.1812
Abstract: Importance Clinical trials of glaucoma therapies focused on protecting the optic nerve have required large sample sizes and lengthy follow-up to detect clinically relevant change due to its slow rate of progression. Whether shorter trials… read more here.
Keywords: glaucoma progression; term assessment; assessment glaucoma; glaucoma ... See more keywords
Minimally Invasive Glaucoma Surgical Techniques for Open-Angle Glaucoma: An Overview of Cochrane Systematic Reviews and Network Meta-analysis.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2021.2351
Abstract: Importance Glaucoma affects more than 75 million people worldwide. Intraocular pressure (IOP)-lowering surgery is an important treatment for this disease. Interest in reducing surgical morbidity has led to the introduction of minimally invasive glaucoma surgeries… read more here.
Keywords: surgery; term; drop free; glaucoma ... See more keywords
Association Between Ganglion Cell Complex Thinning and Vision-Related Quality of Life in Glaucoma.
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DOI: 10.1001/jamaophthalmol.2022.2140
Abstract: Importance Faster structural changes may be associated with worse vision-related quality of life in patients with glaucoma. Objectives To evaluate the association between the rate of ganglion cell complex thinning and the Vision Function Questionnaire… read more here.
Keywords: ganglion cell; vision; glaucoma; cell complex ... See more keywords
Association of High Polygenic Risk With Visual Field Worsening Despite Treatment in Early Primary Open-Angle Glaucoma.
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DOI: 10.1001/jamaophthalmol.2022.4688
Abstract: Importance Irreversible vision loss from primary open-angle glaucoma (POAG) can be prevented through timely diagnosis and treatment, although definitive diagnosis can be difficult in early-stage disease. As a consequence, large numbers of individuals with suspected… read more here.
Keywords: glaucoma; progression; polygenic risk; risk ... See more keywords
A Case of Unilateral Intraocular Pressure Elevation in a Patient With Glaucoma.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2022.4735
Abstract: A 52-year-old man with a history of severe primary open-angle glaucoma in both eyes presented with an intraocular pressure above target in the left eye. A 24-2 Humphrey visual field showed new glaucoma progression. What… read more here.
Keywords: pressure elevation; glaucoma; case unilateral; unilateral intraocular ... See more keywords
Estimating the Length of the Preclinical Detectable Phase for Open-Angle Glaucoma.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2022.5056
Abstract: Importance A 50% reduction of glaucoma-related blindness has previously been demonstrated in a population that was screened for open-angle glaucoma. Ongoing screening trials of high-risk populations and forthcoming low-cost screening methods suggest that such screening… read more here.
Keywords: mean pcdp; open angle; glaucoma; angle glaucoma ... See more keywords