Rare protective variants and glaucoma-relevant cell stressors modulate angiopoietin-like 7 expression.
Sign Up to like & getrecommendations! Published in 2023 at "Human molecular genetics"
DOI: 10.1093/hmg/ddad083
Abstract: Rare missense and nonsense variants in the Angiopoietin-like 7 (ANGPTL7) gene confer protection from primary open-angle glaucoma (POAG), though the functional mechanism remains uncharacterized. Interestingly, larger variant effect size strongly correlates with in silico predictions… read more here.
Keywords: cell stressors; expression; protective variants; angiopoietin like ... See more keywords