A two‐stage model for precise identification and Gleason grading of clinically significant prostate cancer: a hybrid approach
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Medical Radiation Sciences"
DOI: 10.1002/jmrs.841
Abstract: Accurate identification and grading of clinically significant prostate cancer (csPCa, Gleason Score ≥ 7) without invasive procedures remains a significant clinical challenge. This study aims to develop and evaluate a two‐stage model designed for precise Gleason grading.… read more here.
Keywords: gleason grading; gleason; clinically significant; grading clinically ... See more keywords
Establishment of a prognostic risk model for prostate cancer based on Gleason grading and cuprotosis related genes
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-024-05899-9
Abstract: Prostate cancer (PCa) is common in aging males, diagnosed via the Gleason grading system. The study explores the unexamined prognostic value of cuprotosis, a distinct cell death type, alongside Gleason grades in PCa. We explored… read more here.
Keywords: risk model; cancer; prostate cancer; gleason ... See more keywords
Unfavorable Intermediate‐Risk Prostate Cancer and the Odds of Upgrading to Gleason 8 or Higher at Prostatectomy
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Genitourinary Cancer"
DOI: 10.1016/j.clgc.2016.06.001
Abstract: Micro‐Abstract In order to decide whether to administer radiation and a short or long course of androgen deprivation therapy in men with unfavorable intermediate‐risk prostate cancer, multiparametric magnetic resonance imaging could be considered when the… read more here.
Keywords: gleason; score higher; intermediate risk; unfavorable intermediate ... See more keywords
Validation of a Contemporary Five-tiered Gleason Grade Grouping Using Population-based Data.
Sign Up to like & getrecommendations! Published in 2017 at "European urology"
DOI: 10.1016/j.eururo.2016.11.031
Abstract: This population-based study assesses whether a proposed five-tiered Gleason grade grouping (GGG) system predicts prostate cancer-specific mortality (PCSM). Using the Surveillance, Epidemiology, and End Results (SEER) database, we identified 331320 prostate cancer patients who had… read more here.
Keywords: five tiered; gleason; system; population based ... See more keywords
Gleason score 5+3=8 (grade group 4) prostate cancer - a rare occurrence with contemporary grading.
Sign Up to like & getrecommendations! Published in 2020 at "Human pathology"
DOI: 10.1016/j.humpath.2019.11.002
Abstract: Grade Group (GG) 4 prostate cancer includes Gleason scores (GS) 3+5=8, 4+4=8, and 5+3=8. Some studies without pathology re-review of historical cohorts proposed that the presence of pattern 5 worsens prognosis compared to GS 4+4=8… read more here.
Keywords: gleason; grade group; grade; pathology ... See more keywords
Accurate pattern-based extraction of complex Gleason score expressions from pathology reports
Sign Up to like & getrecommendations! Published in 2021 at "Journal of biomedical informatics"
DOI: 10.1016/j.jbi.2021.103850
Abstract: PURPOSE The Gleason score is an important grading factor of prostate cancer. Gleason scores can be extracted from pathology report texts using regular expressions, but previously developed programmes have targeted only relatively simple Gleason score… read more here.
Keywords: gleason; pathology; gleason score; complex gleason ... See more keywords
The prognostic role of tertiary Gleason pattern 5 in a contemporary grading system for prostate cancer
Sign Up to like & getrecommendations! Published in 2017 at "Prostate Cancer and Prostatic Diseases"
DOI: 10.1038/pcan.2016.55
Abstract: BACKGROUND:Recently, a new prostate cancer (PC) grading system has been introduced, where Gleason score (GS) 7 (3+4) and GS 7 (4+3) are categorized into two separate groups. However, GS 7 with tertiary Gleason pattern 5… read more here.
Keywords: bcr; gleason; prostate cancer; grading system ... See more keywords
Pathologist-like explainable AI for interpretable Gleason grading in prostate cancer
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-64712-4
Abstract: The aggressiveness of prostate cancer is primarily assessed from histopathological data using the Gleason scoring system. Conventional artificial intelligence (AI) approaches can predict Gleason scores, but often lack explainability, which may limit clinical acceptance. Here,… read more here.
Keywords: gleason; segmentation; prostate cancer; pattern ... See more keywords
Seminal metabolomics distinguish Gleason grades
Sign Up to like & getrecommendations! Published in 2021 at "Nature Reviews Urology"
DOI: 10.1038/s41585-021-00495-9
Abstract: Metabolomic profiling of seminal fluid might enable differentiation of indolent prostate cancer from aggressive disease, according to a recent study. Semen samples collected from otherwise healthy individuals (n = 13) before infertility treatment and patients… read more here.
Keywords: gleason; seminal metabolomics; prostate cancer; metabolomics distinguish ... See more keywords
A critical evaluation of visual proportion of Gleason 4 and maximum cancer core length quantified by histopathologists
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-73524-z
Abstract: Gleason score 7 prostate cancer with a higher proportion of pattern 4 (G4) has been linked to genomic heterogeneity and poorer patient outcome. The current assessment of G4 proportion uses estimation by a pathologist, with… read more here.
Keywords: cancer core; gleason; estimation; maximum cancer ... See more keywords
Frederic Grant Gleason and the Emerging Chicago Music Scene of the Gilded Age
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Musicological Research"
DOI: 10.1080/01411896.2025.2499805
Abstract: ABSTRACT Little-known composer and music critic Frederic Grant Gleason (1848–1903) persevered in carving out a reputation, for himself and his city through his connection to the Chicago Auditorium (1889), Chicago Symphony Orchestra (1891), and Chicago… read more here.
Keywords: frederic grant; gleason; grant gleason; gleason emerging ... See more keywords