Evaluation of Gleason Grade Group 5 in a Contemporary Prostate Cancer Grading System and Literature Review.
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DOI: 10.1016/j.clgc.2020.08.001
Abstract: INTRODUCTION The aim of this study was to validate contemporary grading systems, in particular, the Gleason grade group (GGG) 5. PATIENTS AND METHODS We retrospectively reviewed the clinicopathologic data of 176 patients who underwent radical prostatectomy… read more here.
Keywords: group; prostate cancer; cancer; grade group ... See more keywords
Focal Therapy Should Not Be Considered for Men with Gleason Grade Group 3-5 Prostate Cancer.
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DOI: 10.1016/j.euf.2019.06.005
Abstract: We argue that there is not enough evidence to safely offer focal therapy to men with Gleason grade group 3-5 prostate cancer. read more here.
Keywords: men gleason; gleason grade; focal therapy; prostate cancer ... See more keywords
Computationally Derived Cribriform Area Index from Prostate Cancer Hematoxylin and Eosin Images Is Associated with Biochemical Recurrence Following Radical Prostatectomy and Is Most Prognostic in Gleason Grade Group 2.
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DOI: 10.1016/j.euf.2021.04.016
Abstract: BACKGROUND The presence of invasive cribriform adenocarcinoma (ICC), an expanse of cells containing punched-out lumina uninterrupted by stroma, in radical prostatectomy (RP) specimens has been associated with biochemical recurrence (BCR). However, ICC identification has only… read more here.
Keywords: index; area; cancer; grade group ... See more keywords
MP81-06 RADIOMIC FEATURES OF PROSTATE CANCER PATIENTS (GLEASON GRADE GROUP = 2) SHOW DIFFERENCES BETWEEN AFRICAN AMERICAN AND CAUCASIAN POPULATIONS ON BI-PARAMETRIC MRI
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DOI: 10.1097/ju.0000000000000973.06
Abstract: INTRODUCTION AND OBJECTIVE: Recent studies tend to suggest that African American (AA) men harbor more aggressive prostate cancer (PCa) than their Caucasian (CA) counterparts which may likely be on account of biological factors. These differences… read more here.
Keywords: gleason grade; cancer; radiomic features; prostate cancer ... See more keywords
Prostate cancer visibility on multiparametric magnetic resonance imaging: high Gleason grade and increased tumour volume are not the only important histopathological features
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DOI: 10.1111/bju.15085
Abstract: Multiparametric magnetic resonance imaging (mpMRI) has excellent pre-biopsy sensitivity for detection of clinically significant prostate cancer, and this now places mpMRI at the forefront of our risk stratification process. Despite this, it appears that not… read more here.
Keywords: resonance imaging; volume; magnetic resonance; prostate cancer ... See more keywords
Primary Gleason grade and Gleason grade group at positive surgical margins: a systematic review and meta‐analysis
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DOI: 10.1111/bju.15316
Abstract: To systematically review and perform a meta‐analysis of studies investigating the role of primary Gleason grade (PGG), Gleason score (GS) or Gleason grade group (GGG) at positive surgical margins (PSMs) after radical prostatectomy (RP) in… read more here.
Keywords: gleason; primary gleason; positive surgical; grade group ... See more keywords
From Cognitive MR-Targeted Fusion Prostate Biopsy to Radical Prostatectomy: Incidence and Predictors of Gleason Grade Group Upgrading in a Chinese Cohort
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DOI: 10.1155/2022/7944342
Abstract: Purpose To access the incidence and predictors of Gleason grade group upgrading from cognitive MR-targeted fusion prostate biopsy to radical prostatectomy in a Chinese cohort. Materials and Methods We included 199 patients in our institution… read more here.
Keywords: prostate; group upgrading; biopsy; gleason grade ... See more keywords
Discriminatory Gleason grade group signatures of prostate cancer: An application of machine learning methods
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DOI: 10.1371/journal.pone.0267714
Abstract: One of the most precise methods to detect prostate cancer is by evaluation of a stained biopsy by a pathologist under a microscope. Regions of the tissue are assessed and graded according to the observed… read more here.
Keywords: gleason grade; grade group; machine learning;
Androgen deprivation therapy and Gleason grade: unravelling implications on survival
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DOI: 10.21037/tcr.2019.04.12
Abstract: The efficacy of concurrent androgen deprivation therapy (ADT) with radiation therapy among patients with high-risk prostate cancer is well documented. A meta-analysis by Kishan et al . (1) compared the effect of ADT duration on… read more here.
Keywords: therapy gleason; deprivation therapy; therapy; androgen deprivation ... See more keywords