Targeting the PI3K/AKT pathway via GLI1 inhibition enhanced the drug sensitivity of acute myeloid leukemia cells
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DOI: 10.1038/srep40361
Abstract: Combination targeted therapy is commonly used to treat acute myeloid leukemia (AML) patients, particularly in refractory/relapse (RR) population. However, concerns have been raised regarding the safety and patient tolerance of combination chemotherapy. It is critical… read more here.
Keywords: acute myeloid; gli1 inhibition; inhibition; drug sensitivity ... See more keywords