Abstract 2371: Stromal androgen signaling acts as tumor niches to drive prostatic basal epithelial progenitor initiated oncogenesis through IGFBP3 mediated IGF1 induced Wnt activation
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DOI: 10.1158/1538-7445.am2023-2371
Abstract: Prostate cancer is the second most common cancer in men worldwide. The current treatment targeting androgen receptor (AR) expressing cells, androgen deprivation therapy (ADT), eventually fails in most prostate cancer patients who consequently develop castration… read more here.
Keywords: igfbp3; igf1; gli1 lineage; tumor ... See more keywords