Biliary YB-1/GLI2 axis facilitates ductular reaction and promotes hepatic stellate cell activation via SPP1/Integrin αvβ1 signaling during liver fibrogenesis.
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DOI: 10.1097/hep.0000000000001458
Abstract: BACKGROUND AIMS Emerging evidence suggests that ductular reactive cells (DRCs)-mediated ductular reaction (DR) accelerates the activation of hepatic stellate cells (HSCs) and contributes to liver fibrogenesis. Previous studies implicated Y-box binding protein 1 (YB-1) in… read more here.
Keywords: integrin; activation; gli2; gli2 axis ... See more keywords