Transcriptome analysis reveals the contribution of oligodendrocyte and radial glia‐derived cues for maintenance of microglia identity
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DOI: 10.1002/glia.24136
Abstract: Microglia are increasingly being recognized as druggable targets in neurodegenerative disorders, and good in vitro models are crucial to address cell biological questions. Major challenges are to recapitulate the complex microglial morphology and their in… read more here.
Keywords: analysis; derived cues; oligodendrocyte radial; glia derived ... See more keywords
Glia-derived exosomes: Promising therapeutic targets.
Sign Up to like & getrecommendations! Published in 2019 at "Life sciences"
DOI: 10.1016/j.lfs.2019.116951
Abstract: Glia is an important component of the nervous system that is involved in neurotransmitter uptake, signal transduction, myelin synthesis, neurodevelopment, and immune response. Exosomes are extracellular vesicles that are secreted from certain types of cells,… read more here.
Keywords: glia derived; therapeutic targets; disease; promising therapeutic ... See more keywords
NG2 glia-derived GABA release tunes inhibitory synapses and contributes to stress-induced anxiety
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DOI: 10.1038/s41467-021-25956-y
Abstract: NG2 glia, also known as oligodendrocyte precursor cells (OPCs), play an important role in proliferation and give rise to myelinating oligodendrocytes during early brain development. In contrast to other glial cell types, the most intriguing… read more here.
Keywords: gaba release; ng2 glia; derived gaba; glia derived ... See more keywords
MicroRNA-28 potentially regulates the photoreceptor lineage commitment of Müller glia-derived progenitors
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DOI: 10.1038/s41598-017-11112-4
Abstract: Retinal degenerative diseases ultimately result into irreversible photoreceptor death or loss. At present, the most promising treatment for these diseases is cell replacement therapy. Müller glia are the major glia in the retina, displaying cardinal… read more here.
Keywords: ller; glia derived; ller glia; mir ... See more keywords
Role of Glia-Derived Extracellular Vesicles in Neurodegenerative Diseases
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DOI: 10.3389/fnagi.2021.765395
Abstract: Extracellular vesicles (EVs), as nano-sized vesicles secreted by almost all cells, have been recognized as the essential transmitter for cell-to-cell communication and participating in multiple biological processes. Neurodegenerative diseases (ND), such as Alzheimer’s disease, Parkinson’s… read more here.
Keywords: extracellular vesicles; glia derived; neurodegenerative diseases; role glia ... See more keywords