The 19S proteasome subunit Rpt5 reversibly associates with cold‐stable microtubules in glial cells at low temperatures
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14307
Abstract: The ubiquitin–proteasome system (UPS) degrades intracellular proteins through the 26S proteasome. We analysed how cold stress affects the UPS in glial cells. Together with a reduction in the 20S proteolytic activity and increased levels of… read more here.
Keywords: stable microtubules; 19s proteasome; subunit; glial cells ... See more keywords
Neuron‐glia crosstalk in neuronal remodeling and degeneration: Neuronal signals inducing glial cell phagocytic transformation in Drosophila
Sign Up to like & getrecommendations! Published in 2022 at "BioEssays"
DOI: 10.1002/bies.202100254
Abstract: Neuronal remodeling is a conserved mechanism that eliminates unwanted neurites and can include the loss of cell bodies. In these processes, a key role for glial cells in events from synaptic pruning to neuron elimination… read more here.
Keywords: neuronal remodeling; cell; glia crosstalk; glial cells ... See more keywords
Neuron–glia interaction in the Drosophila nervous system
Sign Up to like & getrecommendations! Published in 2020 at "Developmental Neurobiology"
DOI: 10.1002/dneu.22737
Abstract: Animals are able to move and react in manifold ways to external stimuli. Thus, environmental stimuli need to be detected, information must be processed, and, finally, an output decision must be transmitted to the musculature… read more here.
Keywords: glia interaction; glial cells; nervous system; neuron glia ... See more keywords
Satellite glial cells in human trigeminal ganglia have a broad expression of functional Toll‐like receptors
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Immunology"
DOI: 10.1002/eji.201746989
Abstract: Toll‐like receptors (TLRs) orchestrate immune responses to a wide variety of danger‐ and pathogen‐associated molecular patterns. Compared to the central nervous system (CNS), expression profile and function of TLRs in the human peripheral nervous system… read more here.
Keywords: toll like; satellite glial; glial cells; trigeminal ganglia ... See more keywords
Suppression of SNARE‐dependent exocytosis in retinal glial cells and its effect on ischemia‐induced neurodegeneration
Sign Up to like & getrecommendations! Published in 2017 at "Glia"
DOI: 10.1002/glia.23144
Abstract: Nervous tissue is characterized by a tight structural association between glial cells and neurons. It is well known that glial cells support neuronal functions, but their role under pathologic conditions is less well understood. Here,… read more here.
Keywords: snare dependent; glial cells; dependent exocytosis; ischemia ... See more keywords
Brain H+/CO2 sensing and control by glial cells
Sign Up to like & getrecommendations! Published in 2022 at "Glia"
DOI: 10.1002/glia.24152
Abstract: Maintenance of constant brain pH is critically important to support the activity of individual neurons, effective communication within the neuronal circuits, and, thus, efficient processing of information by the brain. This review article focuses on… read more here.
Keywords: brain; sensing control; glial cells; co2 sensing ... See more keywords
Endocannabinoid signaling in brain diseases: Emerging relevance of glial cells
Sign Up to like & getrecommendations! Published in 2022 at "Glia"
DOI: 10.1002/glia.24172
Abstract: The discovery of cannabinoid receptors as the primary molecular targets of psychotropic cannabinoid Δ9‐tetrahydrocannabinol (Δ9‐THC) in late 1980s paved the way for investigations on the effects of cannabis‐based therapeutics in brain pathology. Ever since, a… read more here.
Keywords: signaling brain; relevance; brain; glial cells ... See more keywords
Functional adaptation of glial cells at neuromuscular junctions in response to injury
Sign Up to like & getrecommendations! Published in 2022 at "Glia"
DOI: 10.1002/glia.24184
Abstract: Synaptic elements from neuromuscular junctions (NMJs) undergo massive morphological and functional changes upon nerve injury. While morphological changes of NMJ‐associated glia in response to injury has been investigated, their functional properties remain elusive. Perisynaptic Schwann… read more here.
Keywords: adaptation; response injury; neuromuscular junctions; glial cells ... See more keywords
The role of glial cells in Zika virus-induced neurodegeneration.
Sign Up to like & getrecommendations! Published in 2023 at "Glia"
DOI: 10.1002/glia.24353
Abstract: Zika virus (ZIKV) is a strongly neurotropic flavivirus whose infection has been associated with microcephaly in neonates. However, clinical and experimental evidence indicate that ZIKV also affects the adult nervous system. In this regard, in… read more here.
Keywords: induced neurodegeneration; glial cells; zikv; nervous system ... See more keywords
Intracellular accumulation and DNA damage caused by methylmercury in glial cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23170
Abstract: Mercury is widely used in industrial and extractive processes, and the improper disposal of waste or products containing this metal produces a significant impact on ecosystems, causing adverse effects on living organisms, including humans. Exposure… read more here.
Keywords: dna; damage; methylmercury; glial cells ... See more keywords
The latest role of nerve‐specific splicing factor PTBP1 in the transdifferentiation of glial cells into neurons
Sign Up to like & getrecommendations! Published in 2022 at "Wiley Interdisciplinary Reviews: RNA"
DOI: 10.1002/wrna.1740
Abstract: Central nervous system injury diseases can cause the loss of many neurons, and it is difficult to regenerate. The field of regenerative medicine believes that supplementing the missing neurons may be an ideal method for… read more here.
Keywords: cells neurons; latest role; transdifferentiation glial; glial cells ... See more keywords