GlialCAM/MLC1 modulates LRRC8/VRAC currents in an indirect manner: Implications for megalencephalic leukoencephalopathy
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DOI: 10.1016/j.nbd.2018.07.031
Abstract: Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare type of leukodystrophy caused by mutations in either MLC1 or GLIALCAM genes. Previous work indicated that chloride currents mediated by the volume-regulated anion channel (VRAC) and… read more here.
Keywords: mlc1; megalencephalic leukoencephalopathy; vrac currents; glialcam mlc1 ... See more keywords