Mitoxantrone-Loaded PLGA Nanoparticles for Increased Sensitivity of Glioblastoma Cancer Cell to TRAIL-Induced Apoptosis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Pharmaceutical Innovation"
DOI: 10.1007/s12247-021-09551-8
Abstract: Purpose Malignant glioma cells are generally insensitive to TRAIL (tumor necrosis factor-related apoptosis-inducing ligand)-induced apoptosis. In this research, we designed a system containing mitoxantrone (MTX) which is loaded into poly lactic-co-glycolic acid (PLGA) nanoparticles (NPs)… read more here.
Keywords: glioblastoma cancer; cell trail; cancer cell; cell ... See more keywords
Combination of B7H6-siRNA and temozolomide synergistically reduces stemness and migration properties of glioblastoma cancer cells.
Sign Up to like & getrecommendations! Published in 2023 at "Experimental cell research"
DOI: 10.2139/ssrn.4148155
Abstract: Glioblastoma multiforme (GBM) is among the malignant brain tumors of the central nervous system (CNS). The survival of this disease is about 14 months after diagnosis. To date, temozolomide is known as first-line therapy for… read more here.
Keywords: glioblastoma cancer; b7h6 sirna; sirna temozolomide; combination ... See more keywords
Oncolytic Effect of Adenoviruses Serotypes 5 and 6 Against U87 Glioblastoma Cancer Stem Cells
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DOI: 10.21873/anticanres.13815
Abstract: Background/Aim: Oncolytic adenoviruses are promising therapeutic agents against both the bulk of tumor cells and cancer stem cells. The present study intended to test the oncolytic capability of adenovirus serotype 6 (Ad6), which has a… read more here.
Keywords: glioblastoma cancer; stem cells; cancer stem;
Metabolic Rewiring in Glioblastoma Cancer: EGFR, IDH and Beyond
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.901951
Abstract: Glioblastoma multiforme (GBM), a highly invasive and incurable tumor, is the humans’ foremost, commonest, and deadliest brain cancer. As in other cancers, distinct combinations of genetic alterations (GA) in GBM induce a diversity of metabolic… read more here.
Keywords: glioblastoma cancer; metabolic rewiring; rewiring glioblastoma; gbm ... See more keywords