Splicing machinery dysregulation drives glioblastoma development/aggressiveness: oncogenic role of SRSF3
Sign Up to like & getrecommendations! Published in 2020 at "Brain"
DOI: 10.1093/brain/awaa273
Abstract: Fuentes-Fayos et al. show that the expression of spliceosome components and splicing factors is dysregulated in high-grade astrocytomas and glioblastomas. The splicing machinery could be a new source of diagnostic and prognostic biomarkers as well… read more here.
Keywords: splicing machinery; machinery; drives glioblastoma; dysregulation drives ... See more keywords
Macrophages in Glioblastoma Development and Therapy: A Double-Edged Sword
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life12081225
Abstract: Glioblastoma (GBM) is one of the leading lethal tumors, featuring aggressive malignancy and poor outcome to current standard temozolomide (TMZ) or radio-based therapy. Developing immunotherapies, especially immune checkpoint inhibitors, have improved patient outcomes in other… read more here.
Keywords: macrophages glioblastoma; therapy; development therapy; glioblastoma development ... See more keywords