Identification of key modules and hub genes in glioblastoma multiforme based on co‐expression network analysis
Sign Up to like & getrecommendations! Published in 2021 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13078
Abstract: Glioblastoma multiforme (GBM) is the most malignant primary tumour in the central nervous system, but the molecular mechanisms underlying its pathogenesis remain unclear. In this study, data set GSE50161 was used to construct a co‐expression… read more here.
Keywords: analysis; hub genes; glioblastoma multiforme; expression ... See more keywords
Novel targets to overcome antiangiogenesis therapy resistance in glioblastoma multiforme: Systems biology approach and suggestion of therapy by galunisertib
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11859
Abstract: Glioblastoma multiforme (GBM) is a tumor with high microvessel density. Antiangiogenesis therapy (AAT) resistance occurs due to the complex mechanisms involved in angiogenesis, with increased chances of recurrence. The vascular endothelial growth factor (VEGF) pathway… read more here.
Keywords: therapy; resistance; antiangiogenesis therapy; glioblastoma multiforme ... See more keywords
Exosomes to control glioblastoma multiforme: Investigating the effects of mesenchymal stem cell‐derived exosomes on C6 cells in vitro
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11884
Abstract: Glioblastoma multiforme (GBM) is a common, aggressive, fast‐growing tumor of the central nervous system that currently has no effective treatment. Although stem cell therapy has shown promising in vitro achievements, the blood–brain barrier (BBB) has… read more here.
Keywords: cell; stem cell; derived exosomes; mesenchymal stem ... See more keywords
AGAP2‐AS1 serves as an oncogenic lncRNA and prognostic biomarker in glioblastoma multiforme
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DOI: 10.1002/jcb.28180
Abstract: Long noncoding RNA (lncRNA) AGAP2 antisense RNA 1 (AGAP2‐AS1) has been suggested to function as an oncogenic lncRNA in lung cancer, breast cancer, and anaplastic glioma. However, the expression pattern and molecular mechanism of AGAP2‐AS1… read more here.
Keywords: agap2; oncogenic lncrna; glioblastoma multiforme; agap2 as1 ... See more keywords
Glioblastoma Multiforme and Adult Neurogenesis in the Ventricular‐Subventricular Zone: A Review
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DOI: 10.1002/jcp.25502
Abstract: Brain cancers account for read more here.
Keywords: subventricular zone; adult; ventricular subventricular; glioblastoma multiforme ... See more keywords
Glioblastoma multiforme: another potential application for 68Ga-PSMA PET/CT as a guide for targeted therapy
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-018-3934-2
Abstract: A 75-year-old man with a 6-year history of left auditory neuroma was referred for a follow up MRI scan. The MRI scan revealed a known stable neuroma and a 42 × 42 × 58mm abnormal… read more here.
Keywords: psma pet; medicine; pet; glioblastoma multiforme ... See more keywords
Tumor uptake in glioblastoma multiforme after IV injection of [177Lu]Lu-PSMA-617
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-020-04715-z
Abstract: Glioblastoma multiforme (GBM) is the most malignant primary brain tumor with limited treatment options in case of recurrence. Prostate-specific membrane antigen (PSMA) expression was demonstrated in microvascular endothelium of GBM and in vivo confirmed by… read more here.
Keywords: psma 617; treatment; glioblastoma multiforme; psma ... See more keywords
MiR-181b modulates chemosensitivity of glioblastoma multiforme cells to temozolomide by targeting the epidermal growth factor receptor
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuro-Oncology"
DOI: 10.1007/s11060-017-2463-3
Abstract: Temozolomide (TMZ) is a promising chemotherapeutic agent to treat Glioblastoma multiforme (GBM). However, resistance to TMZ develops quickly with a high frequency. The mechanisms underlying GBM cells’ resistance to TMZ are not fully understood. MicroRNAs… read more here.
Keywords: gbm; glioblastoma multiforme; growth factor; tmz ... See more keywords
Prognostic value of NUSAP1 in progression and expansion of glioblastoma multiforme
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DOI: 10.1007/s11060-018-2942-1
Abstract: Nucleolar and spindle-associated protein (NUSAP1) is a microtubule and chromatin-binding protein that stabilizes microtubules to prevent depolymerization, maintains spindle integrity. NUSAP1 could cross-link spindles into aster-like structures, networks and fibers. It has also been found… read more here.
Keywords: gbm; prognostic value; glioblastoma multiforme; nusap1 expression ... See more keywords
Defining a prognostic score based on O6-methylguanine-DNA methyltransferase cut-off methylation level determined by pyrosequencing in patients with glioblastoma multiforme
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DOI: 10.1007/s11060-018-2981-7
Abstract: PurposeEpigenetic variations in the O6-methylguanine-methyltransferase gene had been widely associated with a favorable impact on survival in patients affected by glioblastoma multiforme (GBM). Aim of this study is to explore a scoring system based on… read more here.
Keywords: methylation; determined pyrosequencing; methylation level; glioblastoma multiforme ... See more keywords
Absent in melanoma 2 regulates tumor cell proliferation in glioblastoma multiforme
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DOI: 10.1007/s11060-019-03230-y
Abstract: Inflammation is a key aspect of glioblastoma multiforme (GBM) although it remains unclear how it contributes to GBM pathogenesis. Inflammasomes are intracellular multi-protein complexes that are involved in innate immunity and are activated by cellular… read more here.
Keywords: gbm; glioblastoma multiforme; proliferation; absent melanoma ... See more keywords