LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "glioblastoma stem" as a keyword



Photo from wikipedia

In Vitro Methods for the Study of Glioblastoma Stem-Like Cell Radiosensitivity.

Sign Up to like & get
recommendations! Published in 2021 at "Methods in molecular biology"

DOI: 10.1007/978-1-0716-1225-5_3

Abstract: Ionizing radiation is a critical component of glioblastoma (GBM) therapy. Recent data have implicated glioblastoma stem-like cells (GSCs) as determinants of GBM development, maintenance, and treatment response. Understanding the response of GSCs to radiation should… read more here.

Keywords: radiosensitivity; methods study; vitro methods; stem like ... See more keywords
Photo from wikipedia

m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells

Sign Up to like & get
recommendations! Published in 2017 at "Cell reports"

DOI: 10.1016/j.celrep.2017.02.059

Abstract: Summary RNA modifications play critical roles in important biological processes. However, the functions of N6-methyladenosine (m6A) mRNA modification in cancer biology and cancer stem cells remain largely unknown. Here, we show that m6A mRNA modification… read more here.

Keywords: stem cells; self renewal; renewal tumorigenesis; glioblastoma stem ... See more keywords
Photo by nci from unsplash

MicroRNA-Mediated Dynamic Bidirectional Shift between the Subclasses of Glioblastoma Stem-like Cells.

Sign Up to like & get
recommendations! Published in 2017 at "Cell reports"

DOI: 10.1016/j.celrep.2017.05.040

Abstract: Large-scale transcriptomic profiling of glioblastoma (GBM) into subtypes has provided remarkable insight into the pathobiology and heterogeneous nature of this disease. The mechanisms of speciation and inter-subtype transitions of these molecular subtypes require better characterization to… read more here.

Keywords: like cells; stem like; mediated dynamic; glioblastoma stem ... See more keywords
Photo by dorne_marting from unsplash

The NFL-TBS.40-63 peptide targets and kills glioblastoma stem cells derived from human patients and also targets nanocapsules into these cells.

Sign Up to like & get
recommendations! Published in 2019 at "International journal of pharmaceutics"

DOI: 10.1016/j.ijpharm.2019.05.060

Abstract: Glioblastoma stem cells correspond to brain tumor-initiating cells (BTICs) that have been identified in glioblastoma, the most common and aggressive brain tumor, as responsible for tumor initiation, progression and recurrence due to their resistance to… read more here.

Keywords: tbs peptide; stem; stem cells; nfl tbs ... See more keywords
Photo from wikipedia

PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells.

Sign Up to like & get
recommendations! Published in 2021 at "Molecular cell"

DOI: 10.1016/j.molcel.2021.01.015

Abstract: Aberrant cell proliferation is a hallmark of cancer, including glioblastoma (GBM). Here we report that protein arginine methyltransferase (PRMT) 6 activity is required for the proliferation, stem-like properties, and tumorigenicity of glioblastoma stem cells (GSCs),… read more here.

Keywords: prmt6 methylation; stem cells; stem; glioblastoma stem ... See more keywords
Photo by schluditsch from unsplash

Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance.

Sign Up to like & get
recommendations! Published in 2017 at "Cell stem cell"

DOI: 10.1016/j.stem.2016.11.003

Abstract: Glioblastoma, the most common and aggressive malignant brain tumor, is propagated by stem-like cancer cells refractory to existing therapies. Understanding the molecular mechanisms that control glioblastoma stem cell (GSC) proliferation and drug resistance may reveal… read more here.

Keywords: tolerance; drug; stem cell; stem ... See more keywords
Photo from wikipedia

Reciprocal Signaling between Glioblastoma Stem Cells and Differentiated Tumor Cells Promotes Malignant Progression.

Sign Up to like & get
recommendations! Published in 2018 at "Cell stem cell"

DOI: 10.1016/j.stem.2018.03.011

Abstract: Glioblastoma is the most lethal primary brain tumor; however, the crosstalk between glioblastoma stem cells (GSCs) and their supportive niche is not well understood. Here, we interrogated reciprocal signaling between GSCs and their differentiated glioblastoma cell (DGC)… read more here.

Keywords: tumor cells; stem; stem cells; reciprocal signaling ... See more keywords
Photo from wikipedia

The adaptive transition of glioblastoma stem cells and its implications on treatments

Sign Up to like & get
recommendations! Published in 2021 at "Signal Transduction and Targeted Therapy"

DOI: 10.1038/s41392-021-00491-w

Abstract: Glioblastoma is the most malignant tumor occurring in the human central nervous system with overall median survival time read more here.

Keywords: resistance; stem; stem cells; glioblastoma stem ... See more keywords
Photo by erol from unsplash

BRM270, a Compound from Natural Plant Extracts, Inhibits Glioblastoma Stem Cell Properties and Glioblastoma Recurrence.

Sign Up to like & get
recommendations! Published in 2017 at "Journal of medicinal food"

DOI: 10.1089/jmf.2017.3929

Abstract: Glioblastoma multiforme (GBM) is one of the most aggressive and lethal human brain tumors, and the median survival of patients with GBM is only 14 months. Glioblastoma stem cells (GSCs) are regarded as a main… read more here.

Keywords: brm270 compound; recurrence; compound natural; cell ... See more keywords
Photo from wikipedia

USF1/CD90 signaling in maintaining glioblastoma stem cells and tumor-associated macrophages adhesion.

Sign Up to like & get
recommendations! Published in 2022 at "Neuro-oncology"

DOI: 10.1093/neuonc/noac063

Abstract: BACKGROUND Glioblastoma stem cells (GSCs) and their interplay with tumor-associated macrophages (TAMs) are responsible for malignant growth and tumor recurrence of Glioblastoma (GBM), but the underlying mechanisms are largely unknown. METHODS Cell viability, stemness, migration… read more here.

Keywords: tumor; glioblastoma; glioblastoma stem; stem cells ... See more keywords
Photo from wikipedia

TMIC-22. IDENTIFICATION OF CANCER-ASSOCIATED FIBROBLASTS IN GLIOBLASTOMA and Defining Their Protumoral Effects

Sign Up to like & get
recommendations! Published in 2019 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noz175.1056

Abstract: While cancer-associated fibroblasts (CAFs) and their pro-tumoral effects have been demonstrated in systemic cancers, CAFs had been presumed absent in glioblastoma given the lack of normal fibroblasts in the healthy brain. Here, we show that… read more here.

Keywords: cell; cafs; stem; stem cells ... See more keywords