Abstract 5821: The role ofSMARCAL1loss-of-function mutations in glioblastoma telomere maintenance
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DOI: 10.1158/1538-7445.am2020-5821
Abstract: Malignant tumor cells overcome the restriction of progressive telomere shortening by employing telomere maintenance mechanisms (TMMs) to achieve replicative immortality. Over 80% of human cancers maintain telomere length using the enzyme telomerase, which uses an… read more here.
Keywords: function mutations; mutations glioblastoma; telomere maintenance; function ... See more keywords