Boosting Glioblastoma Therapy with Targeted Pyroptosis Induction.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202207604
Abstract: Glioblastoma (GBM) is a highly aggressive cancer that currently lacks effective treatments. Pyroptosis has emerged as a promising therapeutic approach for cancer, but there is still a need for new pyroptosis boosters to target cancer… read more here.
Keywords: boosting glioblastoma; targeted pyroptosis; therapy targeted; pyroptosis ... See more keywords
Glioblastoma Therapy Using Codelivery of Cisplatin and Glutathione Peroxidase Targeting siRNA from Iron Oxide Nanoparticles.
Sign Up to like & getrecommendations! Published in 2020 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.0c12042
Abstract: Glioblastoma (GBM) is the most common and lethal type of malignant brain tumor in adults. Currently, interventions are lacking, the median overall survival of patients with GBM is less than 15 months, and the postoperative… read more here.
Keywords: iron oxide; oxide nanoparticles; glutathione peroxidase; glioblastoma therapy ... See more keywords
Targeting interleukin-13 receptor α2 (IL-13Rα2) for glioblastoma therapy with surface functionalized nanocarriers
Sign Up to like & getrecommendations! Published in 2022 at "Drug Delivery"
DOI: 10.1080/10717544.2022.2075986
Abstract: Abstract Despite surgical and therapeutic advances, glioblastoma multiforme (GBM) is among the most fatal primary brain tumor that is aggressive in nature. Patients with GBM have a median lifespan of just 15 months when treated… read more here.
Keywords: functionalized nanocarriers; glioblastoma; surface functionalized; glioblastoma therapy ... See more keywords
Radiologic progression of glioblastoma under therapy—an exploratory analysis of AVAglio
Sign Up to like & getrecommendations! Published in 2018 at "Neuro-Oncology"
DOI: 10.1093/neuonc/nox162
Abstract: Background In this exploratory analysis of AVAglio, a randomized phase III clinical study that investigated the addition of bevacizumab (Bev) to radiotherapy/temozolomide in newly diagnosed glioblastoma, we aim to radiologically characterize glioblastoma on therapy until… read more here.
Keywords: glioblastoma; treatment; glioblastoma therapy; progression ... See more keywords
A link closer to glioblastoma therapy
Sign Up to like & getrecommendations! Published in 2017 at "Science Signaling"
DOI: 10.1126/scisignal.aan3515
Abstract: A next-generation mTOR inhibitor combines features of its predecessors to more potently and durably inhibit the growth of glioblastoma in mice. A next-generation mTOR inhibitor combines features of its predecessors to more potently and durably… read more here.
Keywords: glioblastoma therapy; link closer; glioblastoma; closer glioblastoma ... See more keywords
Temozolomide and Other Alkylating Agents in Glioblastoma Therapy
Sign Up to like & getrecommendations! Published in 2019 at "Biomedicines"
DOI: 10.3390/biomedicines7030069
Abstract: The alkylating agent temozolomide (TMZ) together with maximal safe bulk resection and focal radiotherapy comprises the standard treatment for glioblastoma (GB), a particularly aggressive and lethal primary brain tumor. GB affects 3.2 in 100,000 people… read more here.
Keywords: agents glioblastoma; temozolomide alkylating; alkylating agents; treatment ... See more keywords
Natural Compounds in Glioblastoma Therapy: Preclinical Insights, Mechanistic Pathways, and Outlook
Sign Up to like & getrecommendations! Published in 2021 at "Cancers"
DOI: 10.3390/cancers13102317
Abstract: Simple Summary Glioblastoma (GBM) is a tumor of the brain or spinal cord with poor clinical prognosis. Current interventions, such as chemotherapy and surgical tumor resection, are constrained by tumor invasion and cancer drug resistance.… read more here.
Keywords: natural compounds; gbm; compounds glioblastoma; glioblastoma therapy ... See more keywords