Glioblastoma treatment slowly moves toward change: novel druggable targets and translational horizons in 2022
Sign Up to like & getrecommendations! Published in 2023 at "Expert Opinion on Drug Discovery"
DOI: 10.1080/17460441.2023.2174097
Abstract: ABSTRACT Introduction Glioblastoma (GBM) is the most common primary brain tumor in adults. GBM treatment options have been the same for the past 30 years and have only modestly extended survival, despite aggressive multimodal treatments.… read more here.
Keywords: glioblastoma; glioblastoma treatment; slowly moves; treatment slowly ... See more keywords
Tumour Treating Fields in Glioblastoma: Is the treatment tolerable, effective, and practical in UK Patients?
Sign Up to like & getrecommendations! Published in 2021 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noab195.043
Abstract: Tumour Treating Fields (TTF) in combination with standard therapy, prolongs survival in patients with Glioblastoma (GBM). The aim of the current study was to assess the feasibility of integrating TTF into a standard UK neuro-oncology… read more here.
Keywords: fields glioblastoma; treatment; tumour treating; treating fields ... See more keywords
Immunotherapeutic Approaches for Glioblastoma Treatment
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10020427
Abstract: Glioblastoma remains a challenging disease to treat, despite well-established standard-of-care treatments, with a median survival consistently of less than 2 years. In this review, we delineate the unique disease-specific challenges for immunotherapies, both brain-related and… read more here.
Keywords: glioblastoma treatment; approaches glioblastoma; immunotherapeutic approaches;
Recurrent Glioblastoma Treatment: State of the Art and Future Perspectives in the Precision Medicine Era
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10081927
Abstract: Current treatment guidelines for the management of recurrent glioblastoma (rGBM) are far from definitive, and the prognosis remains dismal. Despite recent advancements in the pharmacological and surgical fields, numerous doubts persist concerning the optimal strategy… read more here.
Keywords: recurrent glioblastoma; glioblastoma treatment; treatment; medicine ... See more keywords
Nano-Therapies for Glioblastoma Treatment
Sign Up to like & getrecommendations! Published in 2020 at "Cancers"
DOI: 10.3390/cancers12010242
Abstract: Traditional anti-cancer treatments are inefficient against glioblastoma, which remains one of the deadliest and most aggressive cancers. Nano-drugs could help to improve this situation by enabling: (i) an increase of anti-glioblastoma multiforme (GBM) activity of… read more here.
Keywords: nano therapies; therapies glioblastoma; glioblastoma treatment; tumor ... See more keywords
Obstacles to Glioblastoma Treatment Two Decades after Temozolomide
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14133203
Abstract: Simple Summary Glioblastomas are the most common and aggressive brain tumors in adults, with a median survival of 15 months. Treatment is surgical removal, followed by chemotherapy and/or radiotherapy. Current chemotherapeutics do not kill all… read more here.
Keywords: glioblastoma cells; glioblastoma treatment; obstacles glioblastoma; brain ... See more keywords
Glioblastoma Treatment: State-of-the-Art and Future Perspectives
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23137207
Abstract: (1) Background: Glioblastoma is the most frequent and lethal primary tumor of the central nervous system. Through many years, research has brought various advances in glioblastoma treatment. At this time, glioblastoma management is based on… read more here.
Keywords: glioblastoma treatment; future; state art; treatment ... See more keywords
Ferroptosis Involvement in Glioblastoma Treatment
Sign Up to like & getrecommendations! Published in 2022 at "Medicina"
DOI: 10.3390/medicina58020319
Abstract: Glioblastoma multiforme (GBM) is one of the deadliest brain tumors. Current standard therapy includes tumor resection surgery followed by radiotherapy and chemotherapy. Due to the tumors invasive nature, recurrences are almost a certainty, giving the… read more here.
Keywords: glioblastoma; ferroptosis involvement; involvement glioblastoma; glioblastoma treatment ... See more keywords
Glioblastoma — treatment and obstacles
Sign Up to like & getrecommendations! Published in 2022 at "Reports of Practical Oncology and Radiotherapy"
DOI: 10.5603/rpor.a2022.0076
Abstract: Background Glioblastoma is the most common and aggressive primary tumor in adults. A narrative review of all the relevant papers known was conducted. Materials and methods Reviews, clinical trials, and randomized controlled trials published from… read more here.
Keywords: glioblastoma; glioblastoma treatment; treatment obstacles; radiation ... See more keywords