OS06.7 PI-3Kγ inhibition suppresses glioblastoma tumorigenicity through disruption of an IL11-STAT3-MYC signaling axis between microglia and glioblastoma.
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DOI: 10.1093/neuonc/nox036.041
Abstract: AbstractWhile mutations in isocitrate dehydrogenase (IDH) gene are associated with favorable prognosis in glioblastoma patients, the biologic basis for favorable survival in patients with wild-type IDH (wtIDH) glioblastoma remains poorly understood. We identified that an… read more here.
Keywords: glioblastoma tumorigenicity; glioblastoma; il11; stat3 myc ... See more keywords