Contrast Enhancement Patterns in Pediatric Glioblastomas
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Computer Assisted Tomography"
DOI: 10.1097/rct.0000000000001379
Abstract: Background and Purpose Brain tumors are the most common cause of cancer-related deaths among the pediatric population. Among these, pediatric glioblastomas (GBMs) comprise 2.9% of all central nervous system tumors and have a poor prognosis.… read more here.
Keywords: enhancement patterns; glioblastomas; pediatric glioblastomas; gbms ... See more keywords
Molecular landscape of IDH ‐wild type, pTERT ‐wild type adult glioblastomas
Sign Up to like & getrecommendations! Published in 2022 at "Brain Pathology"
DOI: 10.1111/bpa.13107
Abstract: Telomerase reverse transcriptase (TERT) promoter (pTERT) mutation has often been described as a late event in gliomagenesis and it has been suggested as a prognostic biomarker in gliomas other than 1p19q codeleted tumors. However, the… read more here.
Keywords: adult; glioblastomas; amplification; idhwt ... See more keywords
Ultra-Mutation in IDH Wild-Type Glioblastomas of Patients Younger than 55 Years is Associated with Defective Mismatch Repair, Microsatellite Instability, and Giant Cell Enrichment
Sign Up to like & getrecommendations! Published in 2019 at "Cancers"
DOI: 10.3390/cancers11091279
Abstract: Background: Glioblastomas (GBMs) are classified into isocitrate dehydrogenase (IDH) mutants and IDH wild-types (IDH-wt). This study aimed at identifying the mutational assets of IDH-wt GBMs in patients aged 18–54 years for which limited data are… read more here.
Keywords: glioblastomas; idh wild; idh gbms; microsatellite instability ... See more keywords
Methylome Profiling of PD-L1-Expressing Glioblastomas Shows Enrichment of Post-Transcriptional and RNA-Associated Gene Regulation
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14215375
Abstract: Simple Summary Glioblastomas are highly malignant brain tumors. Despite intensive research, there are no curative therapies available at the present time. Since Programmed Cell Death Ligand 1 (PD-L1) is a promising novel candidate in precision… read more here.
Keywords: expressing glioblastomas; glioblastomas; transcriptional rna; post transcriptional ... See more keywords
The Extracellular Matrix in Glioblastomas: A Glance at Its Structural Modifications in Shaping the Tumoral Microenvironment—A Systematic Review
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15061879
Abstract: Simple Summary The new trends in the research on glioblastomas (GBMs) are focusing on understanding the crosstalk between proper neoplastic tissue and its microenvironment. Against this background, the extracellular matrix (ECM) has been classically linked… read more here.
Keywords: extracellular matrix; review; glioblastomas; systematic review ... See more keywords
Interstitial Photodynamic Therapy of Glioblastomas: A Long-Term Follow-up Analysis of Survival and Volumetric MRI Data
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15092603
Abstract: Simple Summary Glioblastomas are the most common primary malignant brain tumors, with a devastating survival perspective. The treatment concept of interstitial photodynamic therapy (iPDT) enables the light-induced destruction of tumor cells based on the combination… read more here.
Keywords: survival; glioblastomas; therapy; treatment ... See more keywords
STAT5b is a marker of poor prognosis, rather than a therapeutic target in glioblastomas
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Oncology"
DOI: 10.3892/ijo.2022.5414
Abstract: The copy number and mRNA expression of STAT5b were assessed in samples from the TCGA repository of glioblastomas (GBM). The activation of this transcription factor was analyzed on tissue microarrays comprising 392 WHO 2016 GBM… read more here.
Keywords: therapeutic target; marker; glioblastomas; stat5b ... See more keywords
Extracranial Metastasis of IDH-1 Wild Type Glioblastomas.
Sign Up to like & getrecommendations! Published in 2020 at "Turkish neurosurgery"
DOI: 10.5137/1019-5149.jtn.29577-20.1
Abstract: AIM Glioblastomas are the most common malignant brain tumors. Although they are highly infiltrative tumors, they rarely metastasize extracranially. Therefore, this study aimed to identify effects of different immunohistochemical features of glioblastoma seldom observed in… read more here.
Keywords: metastasis; isocitrate dehydrogenase; wild type; glioblastomas ... See more keywords
Epigenetically regulated lncRNAs dissect the intratumoural heterogeneity and facilitate immune evasion of glioblastomas
Sign Up to like & getrecommendations! Published in 2023 at "Theranostics"
DOI: 10.7150/thno.79874
Abstract: Background: Glioblastomas are the most common and malignant central nervous system (CNS) tumors that occupied a highly heterogeneous tumor microenvironment (TIME). Long noncoding RNAs (lncRNAs), whose expression can be modified by DNA methylation, are emerging… read more here.
Keywords: immune evasion; glioblastomas; immune related; immune ... See more keywords