Glioma-associated human endothelial cell-derived extracellular vesicles specifically promote the tumourigenicity of glioma stem cells via CD9
Sign Up to like & getrecommendations! Published in 2019 at "Oncogene"
DOI: 10.1038/s41388-019-0903-6
Abstract: The perivascular niche in glioma is critical for the maintenance of glioma stem cells (GSCs), and tumour-endothelial cell (EC) communication impacts tumourigenesis in ways that are incompletely understood. Here, we show that glioma-associated human endothelial… read more here.
Keywords: stem cells; associated human; glioma stem; glioma ... See more keywords
Overexpression of prothymosin-α in glioma is associated with tumor aggressiveness and poor prognosis
Sign Up to like & getrecommendations! Published in 2022 at "Bioscience Reports"
DOI: 10.1042/bsr20212685
Abstract: Abstract Prothymosin-α (PTMA), a nuclear protein, is strikingly associated with unfavorable clinical outcomes in many cancers. However, no information about its clinical relevance in glioma was available. Therefore in the present study, we evaluated the… read more here.
Keywords: overexpression prothymosin; prothymosin glioma; ptma; glioma ... See more keywords
Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587.
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DOI: 10.1158/0008-5472.can-16-2524
Abstract: Tumor-stromal communications impact tumorigenesis in ways that are incompletely understood. Here, we show that glioma-associated human mesenchymal stem cells (GA-hMSC), a newly identified stromal component of glioblastoma, release exosomes that increase the proliferation and clonogenicity… read more here.
Keywords: stem cells; tumor; glioma stem; stem ... See more keywords
Combinatorial Application of Papain and CD66B for Isolating Glioma-Associated Neutrophils.
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DOI: 10.2174/1568009623666221027101637
Abstract: BACKGROUND Stromal cells in the tumor microenvironment play crucial roles in glioma development. Current methods for isolating tumor-associated stromal cells (such as neutrophils) are inefficient due to the conflict between tissue dissociation and cell surface… read more here.
Keywords: tissue dissociation; glioma associated; associated neutrophils; glioma ... See more keywords
The Role of Myeloid Cells in GBM Immunosuppression
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.887781
Abstract: Gliomas are intrinsic brain tumors that originate from glial cells. Glioblastoma (GBM) is the most aggressive glioma type and resistant to immunotherapy, mainly due to its unique immune environment. Dimensional data analysis reveals that the… read more here.
Keywords: myeloid cells; glioma; role myeloid; glioma associated ... See more keywords