LncRNA UCA1 is necessary for TGF‐β‐induced epithelial–mesenchymal transition and stemness via acting as a ceRNA for Slug in glioma cells
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DOI: 10.1002/2211-5463.12533
Abstract: The 5‐year survival rate of patients with glioma is < 5%, and therefore there is an urgent need to find novel potential targets for facilitating its diagnosis and treatment. The long non‐coding RNA (lncRNA) UCA1… read more here.
Keywords: stemness; glioma; lncrna uca1; slug ... See more keywords
Collateral Effects: The CRISPR‐Cas13a Gene‐Editing System Induces Collateral Cleavage of RNA in Glioma Cells (Adv. Sci. 20/2019)
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DOI: 10.1002/advs.201970124
Abstract: In article number https://doi.org/10.1002/advs.201901299, Chunsheng Kang and co‐workers demonstrate the collateral effect of the CRISPR‐Cas13a system in glioma cells. EGFRvIII is a unique EGFR mutant subtype in glioma, and the CRISPR‐Cas13a system induces death in… read more here.
Keywords: system; crispr cas13a; collateral effects; glioma cells ... See more keywords
Estimation of PKCδ autophosphorylation in U87 MG glioma cells: combination of experimental, conceptual and numerical approaches.
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DOI: 10.1002/jbio.201500332
Abstract: Golgi apparatus (GA) is a center for lipid metabolism and the final target of ceramide pathway, which may result in apoptosis. In this work localization of highly hydrophobic hypericin is followed by time-resolved imaging of… read more here.
Keywords: u87 glioma; pkc autophosphorylation; s645 pkc; glioma cells ... See more keywords
Overexpression of Hsc70 promotes proliferation, migration, and invasion of human glioma cells
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DOI: 10.1002/jcb.28362
Abstract: Migration and invasion are often recognized as the main reasons for the high recurrence and death rates of glioma and limit the efficacy of surgery and other antitumor therapies. In this study, we found over… read more here.
Keywords: glioma; hsc70; migration; glioma cells ... See more keywords
3D-Engineered Scaffolds to Study Microtubes and Localization of Epidermal Growth Factor Receptor in Patient-Derived Glioma Cells.
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DOI: 10.1002/smll.202204485
Abstract: A major obstacle in glioma research is the lack of in vitro models that can retain cellular features of glioma cells in vivo. To overcome this limitation, a 3D-engineered scaffold, fabricated by two-photon polymerization, is… read more here.
Keywords: patient derived; cell; microscopy; glioma cells ... See more keywords
EHD1 promotes the cancer stem cell (CSC)‐like traits of glioma cells via interacting with CD44 and suppressing CD44 degradation
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23592
Abstract: Plenty of evidence has shown that endocytosis plays a key role in cancer progression; however, its effects in the progression of cancer stem cells (CSCs) are still fragmentary. In the present study, we firstly identified… read more here.
Keywords: cd44; like traits; glioma cells; csc like ... See more keywords
STAT Signaling in Glioma Cells.
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DOI: 10.1007/978-3-030-30651-9_10
Abstract: STAT (signal transducers and activators of transcription) are latent cytoplasmic transcription factors that function as downstream effectors of cytokine and growth factor receptor signaling. The canonical JAK/STAT signaling pathway involves the activation of Janus kinases… read more here.
Keywords: signaling glioma; glioma; stat signaling; glioma cells ... See more keywords
Cannabinoid Signaling in Glioma Cells.
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DOI: 10.1007/978-3-030-30651-9_11
Abstract: Cannabinoids are a group of structurally heterogeneous but pharmacologically related compounds, including plant-derived cannabinoids, synthetic substances and endogenous cannabinoids, such as anandamide and 2-arachidonoylglycerol. Cannabinoids elicit a wide range of central and peripheral effects mostly… read more here.
Keywords: signaling glioma; cannabinoid; glioma cells; cannabinoid signaling ... See more keywords
Calcium Signaling in Glioma Cells: The Role of Nucleotide Receptors.
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DOI: 10.1007/978-3-030-30651-9_4
Abstract: Calcium signaling is probably one of the evolutionary oldest and the most common way by which the signal can be transmitted from the cell environment to the cytoplasmic calcium binding effectors. Calcium signal is fast… read more here.
Keywords: calcium signal; glioma cells; nucleotide receptors; calcium ... See more keywords
Rhaponticum carthamoides transformed root extract inhibits human glioma cells viability, induces double strand DNA damage, H2A.X phosphorylation, and PARP1 cleavage
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DOI: 10.1007/s10616-018-0251-3
Abstract: Rhaponticum carthamoides transformed root extract induces double strand DNA damage by increasing the number of phosphorylated H2A.X- and cleaved PARP1-positive U87MG cells and patient-derived IV grade glioma cells. Furthermore, treatment of these cells with root… read more here.
Keywords: transformed root; dna damage; carthamoides transformed; glioma cells ... See more keywords
UMI-77 primes glioma cells for TRAIL-induced apoptosis by unsequestering Bim and Bak from Mcl-1
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DOI: 10.1007/s11010-017-2997-x
Abstract: Malignant glioma is the most common and aggressive form of brain tumor with poor prognosis of survival. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a promising anticancer agent but is insufficient of inducing apoptosis in… read more here.
Keywords: mcl; apoptosis; bim bak; glioma cells ... See more keywords