Antiepileptic drug therapy in autoimmune epilepsy associated with antibodies targeting the leucine‐rich glioma‐inactivated protein 1
Sign Up to like & getrecommendations! Published in 2018 at "Epilepsia Open"
DOI: 10.1002/epi4.12226
Abstract: To characterize seizure semiology and the utility of antiepileptic drug (AED) therapy in leucine‐rich glioma inactivated‐1 ( LGI1‐Ab) autoimmune epilepsy (AE). read more here.
Keywords: leucine rich; autoimmune epilepsy; glioma inactivated; rich glioma ... See more keywords
Asymmetrical manifestation of faciobrachial dystonic seizures in leucine‐rich, glioma‐inactivated 1 antibody encephalitis: A case report
Sign Up to like & getrecommendations! Published in 2020 at "Clinical and Experimental Neuroimmunology"
DOI: 10.1111/cen3.12621
Abstract: Leucine‐rich, glioma‐inactivated (LGI1) antibody encephalitis is a rare autoimmune encephalitis characterized by faciobrachial dystonic seizures (FBDS), temporal lobe epilepsy, prominent short‐term memory deficits and altered mental status. FBDS are very brief, frequent stereotypical dystonic seizures… read more here.
Keywords: leucine rich; dystonic seizures; antibody encephalitis; encephalitis ... See more keywords
A Case of Anti-leucine-rich Glioma-inactivated 1 Protein-antibody Positive Encephalitis with Extensive Unilateral Cerebral Cortex and White Matter Lesions.
Sign Up to like & getrecommendations! Published in 2023 at "Internal medicine"
DOI: 10.2169/internalmedicine.1942-23
Abstract: Encephalitis caused by antibodies targeting the leucine-rich glioma-inactivated 1 protein receptor, which belongs to the anti-voltage-gated potassium channel receptor complex, is characterized by hyponatremia, progressive cognitive impairment, seizures, and psychiatric disorders. The patient initially presented… read more here.
Keywords: rich glioma; leucine rich; cerebral cortex; inactivated protein ... See more keywords
Leucine-rich Glioma-inactivated 1 Encephalitis Followed by Isaacs Syndrome: Alternating Presence of Pathogenic Autoantibodies to Leucine-rich Glioma-inactivated 1 and Contactin-associated Protein-like 2.
Sign Up to like & getrecommendations! Published in 2022 at "Internal medicine"
DOI: 10.2169/internalmedicine.9670-22
Abstract: The coexistence of leucine-rich glioma-inactivated 1 (LGI1) and contactin-associated protein-like 2 (CASPR2) autoantibodies in the same individual is surprisingly often observed. We herein report the first case of LGI1 encephalitis followed by Isaacs syndrome in… read more here.
Keywords: rich glioma; leucine rich; encephalitis; glioma inactivated ... See more keywords
Arterial Spin Labeling Imaging Characteristics of Anti-leucine-rich Glioma-Inactivated 1 Encephalitis: A Qualitative and Quantitative Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2022.850029
Abstract: Background and Significance Autoimmune encephalitis (AE) is a rare group of diseases that can present with stroke-like symptoms. Anti-leucine-rich glioma inactivated 1 (LGI1) encephalitis is an AE subtype that is infrequently associated with neoplasms and… read more here.
Keywords: rich glioma; anti leucine; leucine rich; cbf ... See more keywords
Leucine-Rich Glioma Inactivated 1 Promotes Oligodendrocyte Differentiation and Myelination via TSC-mTOR Signaling
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2018.00231
Abstract: Leucine-rich glioma inactivated 1 (Lgi1), a putative tumor suppressor, is tightly associated with autosomal dominant lateral temporal lobe epilepsy (ADLTE). It has been shown that Lgi1 regulates the myelination of Schwann cells in the peripheral… read more here.
Keywords: oligodendrocyte differentiation; leucine rich; myelination; differentiation ... See more keywords