Dendritic cell vaccines improve the glioma microenvironment: Influence, challenges, and future directions
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5511
Abstract: Gliomas, especially the glioblastomas, are one of the most aggressive intracranial tumors with poor prognosis. This might be explained by the heterogeneity of tumor cells and the inhibitory immunological microenvironment. Dendritic cells (DCs), as the… read more here.
Keywords: microenvironment; dendritic cell; vaccines improve; glioma microenvironment ... See more keywords
Imaging of the glioma microenvironment by TSPO PET
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-021-05276-5
Abstract: Gliomas are highly dynamic and heterogeneous tumours of the central nervous system (CNS). They constitute the most common neoplasm of the CNS and the second most common cause of death from intracranial disease after stroke.… read more here.
Keywords: pet; tspo pet; pet imaging; imaging glioma ... See more keywords
Neuronal activity in the glioma microenvironment
Sign Up to like & getrecommendations! Published in 2017 at "Current Opinion in Neurobiology"
DOI: 10.1016/j.conb.2017.10.009
Abstract: Gliomas are the most common primary brain tumor and high-grade gliomas the leading cause of brain tumor-related death in both children and adults. An appreciation for the crucial role of the nervous system in the… read more here.
Keywords: neuronal activity; activity glioma; glioma; glioma microenvironment ... See more keywords
Quantitative proteomic landscapes of primary and recurrent glioblastoma reveal a protumorigeneic role for FBXO2-dependent glioma-microenvironment interactions.
Sign Up to like & getrecommendations! Published in 2022 at "Neuro-oncology"
DOI: 10.1093/neuonc/noac169
Abstract: BACKGROUND Recent efforts have described the evolution of glioblastoma from initial diagnosis to post-treatment recurrence on a genomic and transcriptomic level. However, the evolution of the proteomic landscape is largely unknown. METHODS Sequential window acquisition… read more here.
Keywords: fbxo2 dependent; dependent glioma; glioma; glioma microenvironment ... See more keywords
The miRNA Content of Exosomes Released from the Glioma Microenvironment Can Affect Malignant Progression
Sign Up to like & getrecommendations! Published in 2020 at "Biomedicines"
DOI: 10.3390/biomedicines8120564
Abstract: Low-grade gliomas (LGG) are infiltrative primary brain tumors that in 70% of the cases undergo anaplastic transformation, deeply affecting prognosis. However, the timing of progression is heterogeneous. Recently, the tumor microenvironment (TME) has gained much… read more here.
Keywords: exosomes released; content exosomes; mirna content; progression ... See more keywords
Immune Landscape in PTEN-Related Glioma Microenvironment: A Bioinformatic Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Brain Sciences"
DOI: 10.3390/brainsci12040501
Abstract: Introduction: PTEN gene mutations are frequently found in the genetic landscape of high-grade gliomas since they influence cell proliferation, proangiogenetic pathways, and antitumoral immune response. The present bioinformatics analysis explores the PTEN gene expression profile… read more here.
Keywords: microenvironment; pten; analysis; glioma microenvironment ... See more keywords
Tumor-Associated Macrophages in Gliomas—Basic Insights and Treatment Opportunities
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14051319
Abstract: Simple Summary Macrophages are a specialized immune cell type found in both invertebrates and vertebrates. Versatile in functionality, macrophages carry out important tasks such as cleaning cellular debris in healthy tissues and mounting immune responses… read more here.
Keywords: glioma microenvironment; associated macrophages; macrophages gliomas; treatment ... See more keywords