IDH mutation in glioma: molecular mechanisms and potential therapeutic targets
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Cancer"
DOI: 10.1038/s41416-020-0814-x
Abstract: Isocitrate dehydrogenase (IDH) enzymes catalyse the oxidative decarboxylation of isocitrate and therefore play key roles in the Krebs cycle and cellular homoeostasis. Major advances in cancer genetics over the past decade have revealed that the… read more here.
Keywords: mutation; glioma molecular; molecular mechanisms; idh mutation ... See more keywords
Visualization of Diagnostic and Therapeutic Targets in Glioma With Molecular Imaging
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.592389
Abstract: Gliomas, particularly high-grade gliomas including glioblastoma (GBM), represent the most common and malignant types of primary brain cancer in adults, and carry a poor prognosis. GBM has been classified into distinct subgroups over the years… read more here.
Keywords: glioma molecular; visualization diagnostic; therapeutic targets; diagnostic therapeutic ... See more keywords