N-Methylpropargylamine-Conjugated Hydroxamic Acids as Dual Inhibitors of Monoamine Oxidase A and Histone Deacetylase for Glioma Treatment.
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DOI: 10.1021/acs.jmedchem.1c01726
Abstract: Glioma treatment remains a challenge with a low survival rate due to the lack of effective therapeutics. Monoamine oxidase A (MAO A) plays a role in glioma development, and MAO A inhibitors reduce glioma growth.… read more here.
Keywords: dual inhibitors; histone; monoamine oxidase; glioma ... See more keywords