The epigenetic–metabolic interplay in gliomagenesis
Sign Up to like & getrecommendations! Published in 2022 at "Open Biology"
DOI: 10.1098/rsob.210350
Abstract: Although tumourigenesis occurs due to genetic mutations, the role of epigenetic dysregulations in cancer is also well established. Epigenetic dysregulations in cancer may occur as a result of mutations in genes encoding histone/DNA-modifying enzymes and… read more here.
Keywords: interplay gliomagenesis; role; epigenetic metabolic; gliomagenesis ... See more keywords
Abstract 2603: Investigating TUSC2 for its tumor suppressive functions in glioblastoma and its role in gliomagenesis
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-2603
Abstract: The role of Tumor Suppressor Candidate 2 (TUSC2) in glioblastoma (GBM) is still poorly understood. Our recent study (Cancer Letters, 2022) reported, for the first time, that TUSC2 functions as a novel tumor suppressor for… read more here.
Keywords: tumor suppressor; tusc2; role; gliomagenesis ... See more keywords
Distinct Transitional States of Glial Progenitors Drive Gliomagenesis.
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DOI: 10.1158/2159-8290.cd-rw2019-058
Abstract: The primitive oligodendrocyte precursor cell (OPC) lineage is a primary contributor to gliomagenesis. read more here.
Keywords: gliomagenesis; glial progenitors; states glial; progenitors drive ... See more keywords
The Genetic Architecture of Gliomagenesis–Genetic Risk Variants Linked to Specific Molecular Subtypes
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DOI: 10.3390/cancers11122001
Abstract: Genome-wide association studies have identified 25 germline genetic loci that increase the risk of glioma. The somatic tumor molecular alterations, including IDH-mutation status and 1p/19q co-deletion, have been included into the WHO 2016 classification system… read more here.
Keywords: risk; genetic risk; glioma; gliomagenesis ... See more keywords