Chromosome arm 1q gain is an adverse prognostic factor in localized and diffuse leptomeningeal glioneuronal tumors with BRAF gene fusion and 1p deletion
Sign Up to like & getrecommendations! Published in 2018 at "Acta Neuropathologica"
DOI: 10.1007/s00401-018-1940-x
Abstract: We previously described a series of localized intramedullary glioneuronal tumors limited to the spinal cord with histomorphologic, immunophenotypic, and molecular characteristics of diffuse leptomeningeal glioneuronal tumor (DLGNT), a newly added provisional entry in the current… read more here.
Keywords: diffuse leptomeningeal; localized spinal; glioneuronal tumors; fusion ... See more keywords
Immune Microenvironment and Lineage Tracing Help to Decipher Rosette-Forming Glioneuronal Tumors: A Multi-Omics Analysis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of neuropathology and experimental neurology"
DOI: 10.1093/jnen/nlac074
Abstract: Rosette-forming glioneuronal tumors (RGNT) are rare low-grade primary central nervous system (CNS) tumors. The methylation class (MC) RGNT (MC-RGNT) delineates RGNT from other neurocytic CNS tumors with similar histological features. We performed a comprehensive molecular… read more here.
Keywords: cell; glioneuronal tumors; forming glioneuronal; analysis ... See more keywords
Use of Trametinib in Children and Young Adults With Progressive Low-grade Glioma and Glioneuronal Tumors
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Pediatric Hematology/Oncology"
DOI: 10.1097/mph.0000000000002598
Abstract: Low-grade gliomas/glioneuronal tumors comprise one-third of all pediatric-type CNS tumors. These tumors are generally caused by activating mutations in the mitogen-activated protein kinase (MAPK) pathway. Targeted drugs, such as trametinib, have shown promise in other… read more here.
Keywords: progressive low; glioneuronal tumors; grade glioma; low grade ... See more keywords
Rosette-forming and papillary glioneuronal tumors - A clinicopathological and molecular analysis.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical neuropathology"
DOI: 10.5414/np301164
Abstract: INTRODUCTION Rosette-forming glioneuronal tumors (RGNT) and papillary glioneuronal tumors (PGNT) account for read more here.
Keywords: rosette forming; glioneuronal tumors; forming papillary; papillary glioneuronal ... See more keywords