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   Articles with "gliosarcoma" as a keyword



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Molecular and clonal evolution in recurrent metastatic gliosarcoma

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recommendations! Published in 2020 at "Cold Spring Harbor Molecular Case Studies"

DOI: 10.1101/mcs.a004671

Abstract: We discuss the molecular evolution of gliosarcoma, a mesenchymal type of glioblastoma (GBM), using the case of a 37-yr-old woman who developed two recurrences and an extracranial metastasis. She was initially diagnosed with isocitrate dehydrogenase… read more here.

Keywords: evolution; treated surgery; metastasis; gliosarcoma ... See more keywords
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Secondary gliosarcoma: the clinicopathological features and the development of a patient-derived xenograft model of gliosarcoma

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recommendations! Published in 2021 at "BMC Cancer"

DOI: 10.1186/s12885-021-08008-y

Abstract: Background Gliosarcoma (GSM) is a distinct and aggressive variant of glioblastoma multiforme (GBM) with worse prognosis and few treatment options. It is often managed with the same treatment modalities with temozolomide (TMZ) as in GBM.… read more here.

Keywords: gsm; derived xenograft; model; gliosarcoma ... See more keywords

An IDH1-mutated primary gliosarcoma: case report.

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recommendations! Published in 2017 at "Journal of neurosurgery"

DOI: 10.3171/2016.2.jns151482

Abstract: The authors present the case of a primary gliosarcoma with an isocitrate dehydrogenase-1 (IDH1) mutation. A 75-year-old man presented with a 3-day history of multiple focal seizures and was found on MRI to have a… read more here.

Keywords: isocitrate dehydrogenase; case; primary gliosarcoma; idh1 ... See more keywords

Can a signature molecular-profile define disparate survival in BRAF-positive Gliosarcoma and identify novel targets for therapeutic intervention?

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recommendations! Published in 2022 at "Journal of Cancer Research and Therapeutics"

DOI: 10.4103/jcrt.jcrt_1900_20

Abstract: Purpose: Gliosarcoma (GS) has a low incidence but is aggressively invasive, with poor-survival. Even though GS is recognized as a different subgroup from glioblastoma (GB), there is no molecular panel available to define its clinical… read more here.

Keywords: htert hmga; define; survival; braf ... See more keywords