N6-methyladenosine regulates metabolic remodeling in kidney aging through transcriptional regulator GLIS1
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DOI: 10.1186/s12915-024-02100-y
Abstract: Age-related kidney impairment, characterized by tubular epithelial cell senescence and renal fibrosis, poses a significant global public health threat. Although N6-methyladenosine (m6A) methylation is implicated in various pathological processes, its regulatory mechanism in kidney aging… read more here.
Keywords: kidney aging; m6a; glis1; metabolic remodeling ... See more keywords
GLIS Family Zinc Finger 1 was First Linked With Preaxial Polydactyly I in Humans by Stepwise Genetic Analysis
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DOI: 10.3389/fcell.2021.781388
Abstract: Background: Preaxial polydactyly (PPD) is one of the most common developmental malformations, with a prevalence of 0.8–1.4% in Asians. PPD is divided into four types, PPD I–IV, and PPD I is the most frequent type.… read more here.
Keywords: glis1; family; etiology; ppd ... See more keywords