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   Articles with "glis3" as a keyword



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Detection of a GLIS3 fusion in an infant with AML refractory to chemotherapy

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recommendations! Published in 2022 at "Cold Spring Harbor Molecular Case Studies"

DOI: 10.1101/mcs.a006220

Abstract: Infants diagnosed with acute myeloid leukemia (AML) frequently harbor cytogenetically cryptic fusions involving KMT2A, NUP98, or GLIS2. Those with AML driven specifically by CBFA2T3::GLIS2 fusions have a dismal prognosis and are currently risk-stratified to receive… read more here.

Keywords: fusion; infant aml; glis3; aml refractory ... See more keywords
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Identification of a novel lncRNA (G3R1) regulated by GLIS3 in pancreatic β-cells.

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recommendations! Published in 2020 at "Journal of molecular endocrinology"

DOI: 10.1530/jme-20-0082

Abstract: Recent advances in high throughput RNA sequencing have revealed that, in addition to messenger RNAs (mRNAs), long non-coding RNAs (lncRNAs) play an important role in the regulation of many cell functions and of organ development.… read more here.

Keywords: mouse pancreatic; g3r1; glis3; identification novel ... See more keywords
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2158-P: GLIS3 Is Crucial for Maintenance of Neonatal ß Cells

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recommendations! Published in 2019 at "Diabetes"

DOI: 10.2337/db19-2158-p

Abstract: The Krupple-like zinc finger transcription factor, GLI-similar 3 (GLIS3), is critical for pancreatic β cell development and insulin production. Mutations and single nucleotide variants in the GLIS3 gene have been linked to the development of… read more here.

Keywords: none; glis3; development; maintenance ... See more keywords
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The gene regulatory molecule GLIS3 in gastric cancer as a prognostic marker and be involved in the immune infiltration mechanism

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recommendations! Published in 2023 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2023.1091733

Abstract: Background Gastric cancer is the most prevalent solid tumor form. Even after standard treatment, recurrence and malignant progression are nearly unavoidable in some cases of stomach cancer. GLIS Family Zinc Finger 3 (GLIS3) has received… read more here.

Keywords: immune infiltration; glis3; analysis; gastric cancer ... See more keywords