Investigation of Global Gene Expression of Human Blastocysts Diagnosed as Mosaic using Next-generation Sequencing
Sign Up to like & getrecommendations! Published in 2022 at "Reproductive Sciences"
DOI: 10.1007/s43032-022-00899-x
Abstract: Embryos are diagnosed as mosaic if their chromosomal copy number falls between euploid and aneuploid. The purpose of this study was to investigate the impact of mosaicism on global gene expression. This study included 42… read more here.
Keywords: global gene; diagnosed mosaic; embryos; gene expression ... See more keywords
Transcriptome analysis reveals global gene expression changes of Chilo suppressalis in response to sublethal dose of chlorantraniliprole.
Sign Up to like & getrecommendations! Published in 2019 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2019.06.129
Abstract: The anthranilic diamide insecticide chlorantraniliprole was widely used for the controlling of Chilo suppressalis in China. Previous studies have revealed sublethal effects of chlorantraniliprole on the development and reproduction of C. suppressalis. In the present study,… read more here.
Keywords: transcriptome analysis; analysis; global gene; chilo suppressalis ... See more keywords
Exploring celiac disease candidate pathways by global gene expression profiling and gene network cluster analysis
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-73288-6
Abstract: Celiac disease (CeD) is a gastrointestinal autoimmune disorder, whose specific molecular basis is not yet fully interpreted. Therefore, in this study, we compared the global gene expression profile of duodenum tissues from CeD patients, both… read more here.
Keywords: global gene; gene expression; celiac disease; expression ... See more keywords
Implications of CpG islands on chromosomal architectures and modes of global gene regulation
Sign Up to like & getrecommendations! Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky147
Abstract: Abstract CpG islands (CGIs) have long been implicated in the regulation of vertebrate gene expression. However, the involvement of CGIs in chromosomal architectures and associated gene expression regulations has not yet been thoroughly explored. By… read more here.
Keywords: gene regulation; cpg islands; chromosomal architectures; global gene ... See more keywords
Exploring Chronic Drug Effects on Microengineered Human Liver Cultures Using Global Gene Expression Profiling
Sign Up to like & getrecommendations! Published in 2017 at "Toxicological Sciences"
DOI: 10.1093/toxsci/kfx059
Abstract: Global gene expression profiling is useful for elucidating a drug's mechanism of action on the liver; however, such profiling in rats is not very sensitive for predicting human drug-induced liver injury, while dedifferentiated monolayers of… read more here.
Keywords: drug; global gene; expression profiling; gene expression ... See more keywords
Identification of aberrant innate and adaptive immunity based on changes in global gene expression in the blood of adults with autism spectrum disorder
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Neuroinflammation"
DOI: 10.1186/s12974-021-02154-7
Abstract: Background Autism spectrum disorder (ASD) is characterized as a neurodevelopmental disorder, and one of the main hypotheses regarding its cause is genetic factors. A previous meta-analysis of seven microarray studies and one RNA sequencing (RNA-seq)… read more here.
Keywords: global gene; rna seq; expression; blood ... See more keywords
Condensin Depletion Causes Genome Decompaction Without Altering the Level of Global Gene Expression in Saccharomyces cerevisiae
Sign Up to like & getrecommendations! Published in 2018 at "Genetics"
DOI: 10.1534/genetics.118.301217
Abstract: Gene expression occurs in the context of chromatin organization, but the extent to which higher-order chromatin compaction affects gene expression remains unknown. Here, Paul et al. show that gene expression and genome compaction can be...… read more here.
Keywords: global gene; gene; condensin inactivation; gene expression ... See more keywords