Investigation of Global Gene Expression of Human Blastocysts Diagnosed as Mosaic using Next-generation Sequencing
Sign Up to like & getrecommendations! Published in 2022 at "Reproductive Sciences"
DOI: 10.1007/s43032-022-00899-x
Abstract: Embryos are diagnosed as mosaic if their chromosomal copy number falls between euploid and aneuploid. The purpose of this study was to investigate the impact of mosaicism on global gene expression. This study included 42… read more here.
Keywords: global gene; diagnosed mosaic; embryos; gene expression ... See more keywords
Transcriptome analysis reveals global gene expression changes of Chilo suppressalis in response to sublethal dose of chlorantraniliprole.
Sign Up to like & getrecommendations! Published in 2019 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2019.06.129
Abstract: The anthranilic diamide insecticide chlorantraniliprole was widely used for the controlling of Chilo suppressalis in China. Previous studies have revealed sublethal effects of chlorantraniliprole on the development and reproduction of C. suppressalis. In the present study,… read more here.
Keywords: transcriptome analysis; analysis; global gene; chilo suppressalis ... See more keywords
Exploring celiac disease candidate pathways by global gene expression profiling and gene network cluster analysis
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-73288-6
Abstract: Celiac disease (CeD) is a gastrointestinal autoimmune disorder, whose specific molecular basis is not yet fully interpreted. Therefore, in this study, we compared the global gene expression profile of duodenum tissues from CeD patients, both… read more here.
Keywords: global gene; gene expression; celiac disease; expression ... See more keywords
Implications of CpG islands on chromosomal architectures and modes of global gene regulation
Sign Up to like & getrecommendations! Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky147
Abstract: Abstract CpG islands (CGIs) have long been implicated in the regulation of vertebrate gene expression. However, the involvement of CGIs in chromosomal architectures and associated gene expression regulations has not yet been thoroughly explored. By… read more here.
Keywords: gene regulation; cpg islands; chromosomal architectures; global gene ... See more keywords
Exploring Chronic Drug Effects on Microengineered Human Liver Cultures Using Global Gene Expression Profiling
Sign Up to like & getrecommendations! Published in 2017 at "Toxicological Sciences"
DOI: 10.1093/toxsci/kfx059
Abstract: Global gene expression profiling is useful for elucidating a drug's mechanism of action on the liver; however, such profiling in rats is not very sensitive for predicting human drug-induced liver injury, while dedifferentiated monolayers of… read more here.
Keywords: drug; global gene; expression profiling; gene expression ... See more keywords
A global gene regulatory program and its region-specific regulator partition neurons into commissural and ipsilateral projection types
Sign Up to like & getrecommendations! Published in 2024 at "Science Advances"
DOI: 10.1126/sciadv.adk2149
Abstract: Understanding the genetic programs that drive neuronal diversification into classes and subclasses is key to understand nervous system development. All neurons can be classified into two types: commissural and ipsilateral, based on whether their axons… read more here.
Keywords: commissural ipsilateral; regulatory program; gene; global gene ... See more keywords
Identification of aberrant innate and adaptive immunity based on changes in global gene expression in the blood of adults with autism spectrum disorder
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Neuroinflammation"
DOI: 10.1186/s12974-021-02154-7
Abstract: Background Autism spectrum disorder (ASD) is characterized as a neurodevelopmental disorder, and one of the main hypotheses regarding its cause is genetic factors. A previous meta-analysis of seven microarray studies and one RNA sequencing (RNA-seq)… read more here.
Keywords: global gene; rna seq; expression; blood ... See more keywords
Condensin Depletion Causes Genome Decompaction Without Altering the Level of Global Gene Expression in Saccharomyces cerevisiae
Sign Up to like & getrecommendations! Published in 2018 at "Genetics"
DOI: 10.1534/genetics.118.301217
Abstract: Gene expression occurs in the context of chromatin organization, but the extent to which higher-order chromatin compaction affects gene expression remains unknown. Here, Paul et al. show that gene expression and genome compaction can be...… read more here.
Keywords: global gene; gene; condensin inactivation; gene expression ... See more keywords
The contribution of BvgR, RisA, and RisS to global gene regulation, intracellular cyclic-di-GMP levels, motility, and biofilm formation in Bordetella bronchiseptica
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2024.1305097
Abstract: Bordetella bronchiseptica is a highly contagious respiratory bacterial veterinary pathogen. In this study the contribution of the transcriptional regulators BvgR, RisA, RisS, and the phosphorylation of RisA to global gene regulation, intracellular cyclic-di-GMP levels, motility,… read more here.
Keywords: risa; risa riss; bvgr risa; gene regulation ... See more keywords
Curcumin-Induced Molecular Mechanisms in U-87 MG Glioblastoma Cells: Insights from Global Gene Expression Profiling
Sign Up to like & getrecommendations! Published in 2025 at "Molecules"
DOI: 10.3390/molecules30102108
Abstract: Curcumin, a major phytochemical derived from Curcuma longa, has been shown to enhance the efficacy of chemotherapeutic agents such as doxorubicin, 5-fluorouracil, and cisplatin by overcoming drug resistance, making it a promising adjunct in the… read more here.
Keywords: gene expression; glioblastoma; molecular mechanisms; curcumin ... See more keywords