Global hypomethylation is an independent prognostic factor in diffuse large B cell lymphoma
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DOI: 10.1002/ajh.24751
Abstract: Global hypomethylation has been linked to disease progression in several cancers, but has not been reported for Diffuse Large B Cell Lymphoma (DLBCL). This study aimed to assess global methylation in DLBCL and describe its… read more here.
Keywords: methylation; global hypomethylation; cfdna; large cell ... See more keywords
The genome-wide mutational consequences of DNA hypomethylation
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DOI: 10.1101/2022.10.04.510776
Abstract: DNA methylation is important for establishing and maintaining cell identity and for genomic stability. This is achieved by regulating the accessibility of regulatory and transcriptional elements and the compaction of subtelomeric, centromeric, and other inactive… read more here.
Keywords: dna methylation; genome wide; mutational consequences; global hypomethylation ... See more keywords