Rat Brain Global Ischemia–Induced Diffusion Changes Revisited: Biophysical Modeling of the Water and NAA MR “Diffusion Signal”
Sign Up to like & getrecommendations! Published in 2022 at "Magnetic Resonance in Medicine"
DOI: 10.1002/mrm.29262
Abstract: To assess changes in intracellular diffusion as a mechanism for the reduction in water ADC that accompanies brain injury. Using NAA as a marker of neuronal cytoplasmic diffusion, NAA diffusion was measured before and after… read more here.
Keywords: diffusion; water; brain; naa diffusion ... See more keywords
Selegiline (l-Deprenyl) Mitigated Oxidative Stress, Cognitive Abnormalities, and Histopathological Change in Rats: Alternative Therapy in Transient Global Ischemia
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Neuroscience"
DOI: 10.1007/s12031-020-01544-5
Abstract: Selegiline (l-deprenyl) is the major drug which is used in the treatment of Parkinson’s disease because of its neurotrophic and antiapoptotic properties. Previous studies suggested that low dose of L-methamphetamine (L-METH) caused lower mortality rate… read more here.
Keywords: global ischemia; transient global; oxidative stress;
Amiloride alleviates neurological deficits following transient global ischemia and engagement of central IL-6 and TNF-α signal.
Sign Up to like & getrecommendations! Published in 2019 at "Current molecular medicine"
DOI: 10.2174/1566524019666190704100444
Abstract: BACKGROUND Central pro-inflammatory cytokine (PIC) signal is involved in neurological deficits after transient global ischemia induced by cardiac arrest (CA). The present study was to examine if blocking acid sensing ion channels (ASICs) using amiloride… read more here.
Keywords: neurological deficits; hippocampus; global ischemia; transient global ... See more keywords