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Published in 2018 at "Nature Reviews Drug Discovery"
DOI: 10.1038/nrd.2018.74
Abstract: How many cancer cell therapies are being developed? To harmonize efforts in this arena, the Cancer Research Institute has curated a database that includes all cell therapies in development.
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Keywords:
landscape cancer;
cell therapy;
cancer cell;
cancer ... See more keywords
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Published in 2022 at "Nature genetics"
DOI: 10.1038/s41588-022-01033-y
Abstract: Genomic surveillance has shaped our understanding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants. We performed a global landscape analysis on SARS-CoV-2 genomic surveillance and genomic data using a collection of country-specific data. Here,…
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Keywords:
sars cov;
cov genomic;
global landscape;
genomic surveillance ... See more keywords
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Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky787
Abstract: Abstract Cytokines are cell-to-cell signaling proteins that play a central role in immune development, pathogen responses, and diseases. Cytokines are highly regulated at the transcriptional level by combinations of transcription factors (TFs) that recruit cofactors…
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Keywords:
cytokine;
landscape mouse;
global landscape;
regulation ... See more keywords
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Published in 2017 at "Blood"
DOI: 10.1182/blood-2017-04-780148
Abstract: Factor XI (FXI) deficiency is an autosomal bleeding disorder, usually posttrauma or postsurgery, characterized by reduced levels of coagulation FXI in plasma. The disease is highly prevalent in Ashkenazi Jews (heterozygote frequency, ∼9%), whereas it…
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Keywords:
coagulation;
factor;
global landscape;
genetic variation ... See more keywords
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1
Published in 2019 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2019.00713
Abstract: Epstein-Barr virus (EBV), a gamma-1 herpesvirus, is carried as a life-long asymptomatic infection by the great majority of individuals in all human populations. Yet this seemingly innocent virus is aetiologically linked to two pre-malignant lymphoproliferative…
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Keywords:
ebv;
lymphoma;
landscape ebv;
global landscape ... See more keywords
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Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.1001807
Abstract: As a new type of post-translational modification (PTM), lysine 2-hydroxyisobutyrylation (Khib) was firstly identified in histones and functioned as a regulator of transactivation in mammals. However, the role of Khib proteins remains to be investigated.…
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Keywords:
landscape hydroxyisobutyrylation;
pancreatic cancer;
modified proteins;
hydroxyisobutyrylation ... See more keywords