Articles with "global landscape" as a keyword



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The global landscape of cancer cell therapy

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Published in 2018 at "Nature Reviews Drug Discovery"

DOI: 10.1038/nrd.2018.74

Abstract: How many cancer cell therapies are being developed? To harmonize efforts in this arena, the Cancer Research Institute has curated a database that includes all cell therapies in development. read more here.

Keywords: landscape cancer; cell therapy; cancer cell; cancer ... See more keywords
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Global landscape of SARS-CoV-2 genomic surveillance and data sharing.

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Published in 2022 at "Nature genetics"

DOI: 10.1038/s41588-022-01033-y

Abstract: Genomic surveillance has shaped our understanding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants. We performed a global landscape analysis on SARS-CoV-2 genomic surveillance and genomic data using a collection of country-specific data. Here,… read more here.

Keywords: sars cov; cov genomic; global landscape; genomic surveillance ... See more keywords
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Global landscape of mouse and human cytokine transcriptional regulation

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Published in 2018 at "Nucleic Acids Research"

DOI: 10.1093/nar/gky787

Abstract: Abstract Cytokines are cell-to-cell signaling proteins that play a central role in immune development, pathogen responses, and diseases. Cytokines are highly regulated at the transcriptional level by combinations of transcription factors (TFs) that recruit cofactors… read more here.

Keywords: cytokine; landscape mouse; global landscape; regulation ... See more keywords
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Exploring the global landscape of genetic variation in coagulation factor XI deficiency.

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Published in 2017 at "Blood"

DOI: 10.1182/blood-2017-04-780148

Abstract: Factor XI (FXI) deficiency is an autosomal bleeding disorder, usually posttrauma or postsurgery, characterized by reduced levels of coagulation FXI in plasma. The disease is highly prevalent in Ashkenazi Jews (heterozygote frequency, ∼9%), whereas it… read more here.

Keywords: coagulation; factor; global landscape; genetic variation ... See more keywords
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The Global Landscape of EBV-Associated Tumors

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Published in 2019 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2019.00713

Abstract: Epstein-Barr virus (EBV), a gamma-1 herpesvirus, is carried as a life-long asymptomatic infection by the great majority of individuals in all human populations. Yet this seemingly innocent virus is aetiologically linked to two pre-malignant lymphoproliferative… read more here.

Keywords: ebv; lymphoma; landscape ebv; global landscape ... See more keywords
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Global landscape of 2-hydroxyisobutyrylation in human pancreatic cancer

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Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.1001807

Abstract: As a new type of post-translational modification (PTM), lysine 2-hydroxyisobutyrylation (Khib) was firstly identified in histones and functioned as a regulator of transactivation in mammals. However, the role of Khib proteins remains to be investigated.… read more here.

Keywords: landscape hydroxyisobutyrylation; pancreatic cancer; modified proteins; hydroxyisobutyrylation ... See more keywords