Global profiling of lysine succinylation in human lungs
Sign Up to like & getrecommendations! Published in 2022 at "PROTEOMICS"
DOI: 10.1002/pmic.202100381
Abstract: The lysine succinylation (Ksucc) is involved in many core energy metabolism pathways and affects the metabolic process in mitochondria, making this modification highly valuable for studying diseases related to mitochondrial disorders. In this paper, we… read more here.
Keywords: human lungs; succinylation human; succinylation; global profiling ... See more keywords
Global profiling of the alternative splicing landscape reveals transcriptomic diversity during the early phase of enterovirus 71 infection.
Sign Up to like & getrecommendations! Published in 2020 at "Virology"
DOI: 10.1016/j.virol.2020.06.011
Abstract: The alteration of host cell splicing is a major strategy favouring viral replication; however, the interaction between human tonsillar epithelial cells (HTECs) and enterovirus 71 (EV71) has not been fully elucidated. Here, a total of… read more here.
Keywords: global profiling; infection; alternative splicing; transcriptomic diversity ... See more keywords
Iridium Isotope Tag-Assisted LC-MS Method for Global Profiling and Quantification of Nonvolatile Serum Fatty Acids in Nonalcoholic Fatty Liver Mice.
Sign Up to like & getrecommendations! Published in 2025 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.4c05310
Abstract: Highly accurate and sensitive measurements of fatty acids (FAs) in biological samples are essential for advancing our understanding of their diverse biofunctions. In this work, based on the characteristic isotope pattern of iridium (191/193Ir), we… read more here.
Keywords: mice; iridium; quantification; serum ... See more keywords
Global profiling of RNA-binding protein target sites by LACE-seq.
Sign Up to like & getrecommendations! Published in 2021 at "Nature cell biology"
DOI: 10.1038/s41556-021-00696-9
Abstract: RNA-binding proteins (RBPs) have essential functions during germline and early embryo development. However, current methods are unable to identify the in vivo targets of a RBP in these low-abundance cells. Here, by coupling RBP-mediated reverse… read more here.
Keywords: global profiling; profiling rna; rna binding; lace seq ... See more keywords
Global profiling of polyketide synthases in facultative multicellular eukaryotes.
Sign Up to like & getrecommendations! Published in 2025 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2515852122
Abstract: Polyketides represent a structurally diverse class of natural products with a wide range of biological functions, including antimicrobial activity, defense responses, developmental regulation, pigmentation, and intercellular and intracellular communication signals. The social amoeba Dictyostelium discoideum… read more here.
Keywords: profiling polyketide; polyketide synthases; profiling; synthases facultative ... See more keywords
Global profiling of lysine-malonylated proteins in rice elucidates the immune-regulatory mechanisms of malonylation under herbivore or viral stresses.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of integrative plant biology"
DOI: 10.1111/jipb.70050
Abstract: Lysine malonylation (Kmal), an evolutionarily conserved post-translational modification, serves as a critical regulator of cellular processes including transcriptional control, metabolic coordination, and enzyme activation. While Kmal sites have been mapped in rice (Oryza sativa L.)… read more here.
Keywords: rice; malonylated proteins; lysine malonylated; malonylation ... See more keywords