MIG1 as a positive regulator for the histidine biosynthesis pathway and as a global regulator in thermotolerant yeast Kluyveromyces marxianus
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DOI: 10.1038/s41598-019-46411-5
Abstract: Kmmig1 as a disrupted mutant of MIG1 encoding a regulator for glucose repression in Kluyveromyces marxianus exhibits a histidine-auxotrophic phenotype. Genome-wide expression analysis revealed that only HIS4 in seven HIS genes for histidine biosynthesis was… read more here.
Keywords: kluyveromyces marxianus; regulator; histidine biosynthesis; global regulator ... See more keywords
Identification of the RNA-binding domain-containing protein RbpA that acts as a global regulator of the pathogenicity of Streptococcus suis serotype 2
Sign Up to like & getrecommendations! Published in 2022 at "Virulence"
DOI: 10.1080/21505594.2022.2103233
Abstract: ABSTRACT Streptococcus suis serotype 2 (SS2), an emerging zoonotic pathogen, causes swine diseases and human cases of streptococcal toxic shock syndrome. RNA-binding proteins (RBPs) can modulate gene expression through post-transcriptional regulation. In this study, we… read more here.
Keywords: rna binding; suis serotype; pathogenicity; streptococcus suis ... See more keywords
Identification of a global regulator and its involvement in the regulation network of rubber degradation in Gordonia polyisoprenivorans VH2.
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DOI: 10.1128/aem.00774-20
Abstract: A cAMP receptor protein (CRPVH2) was detected as global regulator in Gordonia polyisoprenivorans VH2 and was supposed to participate in the network regulating poly(cis-1,4-isoprene) degradation as novel key regulator. CRPVH2 shares a sequence identity of… read more here.
Keywords: global regulator; regulation; rubber; crpvh2 ... See more keywords
Mutation of MtrA at the Predicted Phosphorylation Site Abrogates Its Role as a Global Regulator in Streptomyces venezuelae
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DOI: 10.1128/spectrum.02131-21
Abstract: Although phosphorylation has been shown to be essential for the activation of many response regulator proteins of two-component systems, the role of the phosphorylation site in the function of the global regulator MtrA in the… read more here.
Keywords: mtra; site; phosphorylation; global regulator ... See more keywords
Overexpression of Global Regulator SCrp Leads to the Discovery of New Angucyclines in Streptomyces sp. XS-16
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DOI: 10.3390/md21040240
Abstract: Six angucyclines including three unreported compounds (1–3) were isolated from Streptomyces sp. XS-16 by overexpressing the native global regulator of SCrp (cyclic AMP receptor). The structures were characterized based on nuclear magnetic resonance (NMR) and… read more here.
Keywords: regulator scrp; scrp leads; leads discovery; global regulator ... See more keywords