SutA is a Global Transcriptional Regulator Operating during Slow Growth in Pseudomonas Aeruginosa
Sign Up to like & getrecommendations! Published in 2017 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.23840
Abstract: Chronic Pseudomonas aeruginosa infections, a major cause of morbidity and mortality for CF patients, are highly resistant to antibiotic treatment, and many lines of evidence suggest that this is due in part to slow-growing states… read more here.
Keywords: slow growth; global transcriptional; pseudomonas aeruginosa; suta global ... See more keywords
Transcriptional changes through menstrual cycle reveal a global transcriptional derepression underlying the molecular mechanism involved in the window of implantation.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular human reproduction"
DOI: 10.1093/molehr/gaab027
Abstract: The human endometrium is a dynamic tissue that only is receptive to host the embryo during a brief time in the middle secretory phase, called the window of implantation (WOI). Despite its importance, regulation of… read more here.
Keywords: global transcriptional; menstrual cycle; gene expression; cycle ... See more keywords
Bacterial genome architecture shapes global transcriptional regulation by DNA supercoiling
Sign Up to like & getrecommendations! Published in 2019 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkz300
Abstract: Abstract DNA supercoiling acts as a global transcriptional regulator in bacteria, that plays an important role in adapting their expression programme to environmental changes, but for which no quantitative or even qualitative regulatory model is… read more here.
Keywords: transcription; global transcriptional; dna; dna supercoiling ... See more keywords
Cyclin D1 overexpression induces global transcriptional downregulation in lymphoid neoplasms
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Investigation"
DOI: 10.1172/jci96520
Abstract: Cyclin D1 is an oncogene frequently overexpressed in human cancers that has a dual function as cell cycle and transcriptional regulator, although the latter is widely unexplored. Here, we investigated the transcriptional role of cyclin… read more here.
Keywords: overexpression; global transcriptional; cyclin overexpression; cyclin ... See more keywords
Complex genetic and epigenetic regulation deviates gene expression from a unifying global transcriptional program
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1007353
Abstract: Environmental or genetic perturbations lead to gene expression changes. While most analyses of these changes emphasize the presence of qualitative differences on just a few genes, we now know that changes are widespread. This large-scale… read more here.
Keywords: global transcriptional; gene expression; expression; regulation ... See more keywords
Global transcriptional regulation of innate immunity by ATF-7 in C. elegans
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1007830
Abstract: The nematode Caenorhabditis elegans has emerged as a genetically tractable animal host in which to study evolutionarily conserved mechanisms of innate immune signaling. We previously showed that the PMK-1 p38 mitogen-activated protein kinase (MAPK) pathway… read more here.
Keywords: innate immunity; global transcriptional; atf; regulation ... See more keywords
Global transcriptional regulator FNR regulates the pyruvate cycle and proton motive force to play a role in aminoglycosides resistance of Edwardsiella tarda
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.1003586
Abstract: Bacterial metabolism is related to resistance and susceptibility to antibiotics. Fumarate and nitrate reduction regulatory protein (FNR) is a global transcriptional regulator that regulates metabolism. However, the role of FNR in antibiotic resistance is elusive.… read more here.
Keywords: cycle; role; fnr; edwardsiella tarda ... See more keywords
Global transcriptional responses of pneumococcus to human blood components and cerebrospinal fluid
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.1060583
Abstract: Streptococcus pneumoniae (pneumococcus) is a leading cause of severe invasive infectious diseases such as sepsis and meningitis. Understanding how pneumococcus adapts and survive in the human bloodstream environment and cerebrospinal fluid (CSF) is important for… read more here.
Keywords: blood components; pneumococcus human; cerebrospinal fluid; human blood ... See more keywords